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Giants vs. Cubs Odds & Betting Predictions - May 5, 2025

Giants at Cubs

11:40 pm • NBCS-BA

San Francisco Giants

22-14
2
2 - 9

Chicago Cubs

22-14
9
Starting Pitchers
pitcherteameraw-l
Matthew Boyd logoM.BoydChicago Cubs logo2.753-2
Landen Roupp logoL.RouppSan Francisco Giants logo4.892-3

Giants at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Giants
22-14
+1.5
+1.5-151
o7.5-112
+147
Cubs
22-14
u7.5
-1.5+125
u7.5-108
-176
location pinMonday 11:40 p.m.
May 05, 2025
Wrigley FieldChicago
Giants vs. Cubs Expert Picks
The Degenerate
The Degenerate
Last 30d: 122-174-4 (-4.8u)
SF +140
0.5u
Austin Pendergrass
Austin Pendergrass
Last 30d: 86-134-2 (-36.5u)
CHC -160 (F5)
0.63u
Boomer Betz
Boomer Betz
Last 30d: 174-182-4 (+49.8u)
CHC -140
0.71u
Brian Bitler
Brian Bitler
Last 30d: 81-102-0 (-68.7u)
Under 7.5-110
3u
Moneyline Hacks
Moneyline Hacks
Last 30d: 131-95-3 (+61.5u)
Under 7.5-105
1u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG Link to VIP (Copy &Paste): https://linktr.ee/moneylinehacks%F0%9F%94%A560% OFF with promo code: Hacks60
Sean Zerillo
Sean Zerillo
Last 30d: 174-165-18 (+1.4u)
CHC -142
0.5u
Bet to -150
Under 7.5-115
0.58u
Bet to -125

Giants vs. Cubs Previews & Analysis

  • Giants vs Cubs: Trust These Starters article feature image

    Giants vs Cubs: Trust These Starters

    Doug Ziefel•
    May 5, 2025 UTC
  • Monday's Biggest MLB Betting Model Edge (By Far) article feature image

    Monday's Biggest MLB Betting Model Edge (By Far)

    PJ Walsh•
    May 5, 2025 UTC
  • Zerillo's MLB Predictions & Monday Betting Card article feature image

    Zerillo's MLB Predictions & Monday Betting Card

    Sean Zerillo•
    May 5, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Giants vs. Cubs Public Betting Percentages

Away Logo

Giants

Public

Home Logo

Cubs

17%

Bets%

83%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Cubs are 4-1 in their last 5 games.
  • Cubs are 4-1 in their last 5 games against the spread
  • Cubs are 11-8 in their road games against the spread
  • The totals have gone OVER in 3 of Cubs' last 5 games
  • The totals have gone OVER in 12 of Cubs' 17 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs		20-169-811-812-88-8
Giants		16-208-98-1110-125-8

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs		21-13-212-59-8-211-8-110-5-1
Giants		21-14-17-1014-4-19-1311-1-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs		22-1410-712-714-68-8
Giants		22-1412-510-915-76-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 4th@MILL 0-4-1.5 LU 8MIL -115
May 3rd@MILW 6-2-1.5 WU 8.5CHC -118
May 3rd@MILW 10-0-1.5 WO 9CHC -125
May 1st@PITW 8-3+1.5 WO 8CHC +107
Apr 30th@PITL 3-4-1.5 LU 9PIT -176

Giants vs. Cubs Injury Updates

Giants Injuries

  • Tom Murphy
    C

    Murphy is out with back

    Out

  • Jerar Encarnacion
    RF

    Encarnacion is out with hand

    Out

  • Casey Schmitt
    1B

    Casey Schmitt (side) scratched Friday.

    Out

Cubs Injuries

  • Drew Pomeranz
    RP

    Pomeranz is out with elbow

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

See more MLB Injuries Right Arrow
Giants vs. Cubs Box Score
Giants Player Stats
Projected
PITCHERPCIPKER
Landen Roupp logoRL.Roupp, P77542
Hayden Birdsong logoRH.Birdsong, P290.102
Spencer Bivens logoRS.Bivens, P292.210
HITTERSH-ABRHRRBI
Heliot Ramos logo1H.Ramos, LF0-4000
Willy Adames logo2W.Adames, SS0-4000
Jung Hoo Lee logo3J.Lee, CF1-4000
Matt Chapman logo4M.Chapman, 3B2-3100
Brett Wisely logo4B.Wisely, 2B0-1000
Wilmer Flores logo5W.Flores, DH1-4000
Luis Matos logo6L.Matos, RF1-4112
David Villar logo7D.Villar, 1B1-3000
Patrick Bailey logo8P.Bailey, C1-3000
Christian Koss logo9C.Koss, 2B0-3000
Christian Koss logo9C.Koss, 3B0-3000
Cubs Player Stats
Projected
PITCHERPCIPKER
Matthew Boyd logoLM.Boyd, P94672
Caleb Thielbar logoLC.Thielbar, P10120
Gavin Hollowell logoRG.Hollowell, P31210
HITTERSH-ABRHRRBI
Ian Happ logo1I.Happ, LF1-3113
Vidal Brujan logo1V.Brujan, LF0-1000
Kyle Tucker logo2K.Tucker, RF0-4000
Seiya Suzuki logo3S.Suzuki, DH1-5002
Michael Busch logo4M.Busch, 1B0-3000
Carson Kelly logo5C.Kelly, C1-4111
Pete Crow-Armstrong logo6P.Crow-Armstrong, CF1-4200
Nico Hoerner logo7N.Hoerner, 2B1-4200
Dansby Swanson logo8D.Swanson, SS3-4202
Nicky Lopez logo9N.Lopez, 3B1-3101

Giants vs. Cubs Odds Comparison

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Giants at Cubs Team Totals

MatchupOverUnder
Giants
22-14
o3-115
u3-111
Cubs
22-14
o3.5-146
u3.5+115