Jessica Andrade vs. Cynthia Calvillo UFC 266 Odds, Pick & Prediction: How to Bet PPV Opener (Saturday, Sept. 25)

Jessica Andrade vs. Cynthia Calvillo UFC 266 Odds, Pick & Prediction: How to Bet  PPV Opener (Saturday, Sept. 25) article feature image
Credit:

Jeff Bottari/Zuffa LLC. Pictured (L-R): UFC fighters Jessica Andrade of Brazil and Cynthia Calvillo.

  • The opening fight on the pay-per-view portion of UFC 266 features Jessica Andrade and Cynthia Calvillo.
  • Andrade is the favorite and certainly the more violent finisher, but Sean Zerillo sees value in betting Calvillo.
  • Read below for his fight analysis and pick.

Jessica Andrade vs. Cynthia Calvillo Odds

Andrade Odds
-260
Calvillo Odds
+215
Over/Under
2.5 (-156 / +122)
Venue
T-Mobile Arena
Time
Approx. 10 p.m. ET
Channel
ESPN PPV
Odds via FanDuel. Get up-to-the-minute UFC odds here.

The UFC 266 main card opens with a women's flyweight matchup featuring the No. 1-ranked contender in the division, Jessica Andrade, and No. 5-ranked Cynthia Calvillo.

Both women are coming off a loss in their most recent fights and both hope to get a shot at the champion Valentina Shevchenko, who is defending her title in the co-main event.

Below I preview the betting odds and break down the matchup for Saturday's fight. For more analysis on the rest of the card, you can also check out my projections for the entire slate.

Tale of the Tape

AndradeCalvillo
Record21-99-2-1
Avg. Fight Time10:0613:32
Height5'1"5'4"
Weight (pounds)125 lbs.125 lbs.
Reach (inches)62"64"
StanceOrthodoxOrthodox
Date of birth9/25/917/13/87
Sig Strikes Per Min6.154.18
SS Accuracy50%41%
SS Absorbed Per Min5.203.52
SS Defense52%67%
Take Down Avg2.971.85
TD Acc55%44%
TD Def66%71%
Submission Avg0.41.1

I fully expected to back Andrade before diving into this fight, but I came out on the other side of it backing Calvillo because her decision prop offers substantial value.

While Andrade has big advantages in aggression and power, in addition to excellent wrestling (2.97 takedowns per 15 minutes, 55% accuracy), and superior striking metrics (+0.95 to +0.66 strike differential), Calvillo has the height (+3 inches), reach (+2 inches), and offensive grappling of her own (1.85 takedowns per 15 minutes, 44% accuracy) to trouble Andrade.

The Brazilian typically doesn't spend much time being controlled (Valentina Shevchenko had to take her down seven times before finishing her), but Calvillo has the skillset to do just that and she should be able to use her length to work off of her jab from the outside.

While Andrade is the far better, and more powerful striker in the pocket, she's the one who needs to close that distance, whereupon Calvillo may immediately look to shoot for a takedown.

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Andrade vs. Calvillo Pick

Andrade offers significantly higher finishing upside on the feet, and is much more likely to win this fight violently. If Calvillo cannot secure takedowns, she’s very likely to lose this fight by knockout. That factor alone makes betting on the underdog side uncomfortable.

Still, Calvillo has an opportunity to outpoint her opponent with volume and control time, and I cannot pass up the opportunity to play her juicy decision prop since the minute-winning could be relatively even here.

don’t project value on either side of the moneyline or the total, but I did project Calvillo’s odds to win by decision at +340, and I would play that prop at +350 or better, and FanDuel currently has the best line.

The Pick: Cynthia Calvillo wins by Decision (+490, 0.5u)

About the Author
Sean is a Staff Writer at The Action Network and a lawyer in the state of New York. He primarily covers baseball, synthesizing advanced metrics with traditional scouting techniques, and believes that Bartolo Colón's home run was the single greatest athletic achievement of our time.

Follow Sean Zerillo @SeanZerillo on Twitter/X.

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