Week 1 of the 2021 NFL preseason gets underway on Thursday, Aug. 12 and includes 16 matchups throughout the week.
While confusing, the actual start of the 2021 NFL preseason is one week prior when the Dallas Cowboys take on the Pittsburgh Steelers in the Pro Football Hall of Fame Game (click here to see HOF Game odds), but that matchup is basically treated as a standalone game prior to the start of Week 1.
With this in mind, let's take a look at NFL preseason Week 1 odds, including spreads, over/unders, date and times for each game.
NFL Preseason Week 1 Odds
*Odds via PointsBet as of Aug. 4
Washington Football Team vs. New England Patriots
Aug. 12 | 7:30 p.m. ET
Spread: Washington -2
Over/Under: 35
Pittsburgh Steelers vs. Philadelphia Eagles
Aug. 12 | 7:30 p.m. ET
Spread: Eagles -1
Over/Under: 33.5
Tennessee Titans vs. Atlanta Falcons
Aug. 13 | 7 p.m. ET
Spread: Titans -1
Over/Under: 38
Buffalo Bills vs. Detroit Lions
Aug. 13 | 7 p.m. ET
Spread: Bills -2
Over/Under: 37
Dallas Cowboys vs. Arizona Cardinals
Aug. 13 | 10 p.m. ET
Spread: Cardinals -2
Over/Under: 40
Miami Dolphins vs. Chicago Bears
Aug. 14 | 1 p.m. ET
Spread: Bears -3.5
Over/Under: 34.5
Denver Broncos vs. Minnesota Vikings
Aug. 14 | 4 p.m. ET
Spread: Vikings -1.5
Over/Under: 34.5
New Orleans Saints vs. Baltimore Ravens
Aug. 14 | 7 p.m. ET
Spread: Ravens -3
Over/Under: 35.5
Cleveland Browns vs. Jacksonville Jaguars
Aug. 14 | 7 p.m. ET
Spread: Browns -3
Over/Under: 37.5
Cincinnati Bengals vs. Tampa Bay Buccaneers
Aug. 14 | 7:30 p.m. ET
Spread: Buccaneers -6
Over/Under: 33.5
New York Jets vs. New York Giants
Aug. 14 | 7:30 p.m. ET
Spread: Giants -1.5
Over/Under: 34.5
Houston Texans vs. Green Bay Packers
Aug. 14 | 8 p.m. ET
Spread: Packers -3
Over/Under: 33.5
Kansas City Chiefs vs. San Francisco 49ers
Aug. 14 | 8:30 p.m. ET
Spread: 49ers -1.5
Over/Under: 36.5
Seattle Seahawks vs. Las Vegas Raiders
Aug. 14 | 9 p.m. ET
Spread: Raiders -1.5
Over/Under: 37.5
Los Angeles Chargers vs. Los Angeles Rams
Aug. 14 | 10 p.m. ET
Spread: Chargers -2
Over/Under: 34.5
Carolina Panthers vs. Indianapolis Colts
Aug. 15 | 1 p.m. ET
Spread: Colts -2
Over/Under: 34
