49ers vs Seahawks Odds, Spread, Total | NFL Thursday Night Football

49ers vs Seahawks Odds, Spread, Total | NFL Thursday Night Football article feature image
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Getty Images. Pictured: Brock Purdy, Geno Smith.

49ers vs Seahawks Odds for NFL Thursday Night Football

49ers Logo
Thursday, Oct 10
8:15 p.m. ET
Amazon Prime Video
Seahawks Logo
49ers Odds
SpreadTotalMoneyline
-3
-120
46.5
-110o / -110u
-165
Seahawks Odds
SpreadTotalMoneyline
+3
+100
46.5
-110o / -110u
+140
Odds via bet365. Get up-to-the-minute NFL odds here.
bet365 Logo

The 49ers (2-3) face the Seahawks (3-2) in Week 6 of the NFL season, with kickoff set for 8:15 p.m. ET at Lumen Field in Seattle. Here's an early look at the 49ers vs. Seahawks odds, spread and total for this Sunday afternoon matchup.

The 49ers are three-point favorites over the Seahawks in the latest NFL odds for Week 6, with the over/under set at 46.5.

49ers

The 49ers were blanked in the second half of their Week 5 loss, blowing a 23-10 lead as they fell 24-23.

Their four drives in the half ended in an interception, downs, fumble and another interception. San Francisco is 2-3, both SU and ATS.

Seahawks

Seattle fell 29-20 to a shorthanded Giants team that flew across the country. The offensive line failed them, as Geno Smith was sacked seven times.

Meanwhile, they couldn’t get the ground game going as Kenneth Walker had five carries for 19 yards and Zach Charbonnet two carries for 11. Seattle’s dropped two in a row to move to 3-2 SU but are just 1-3-1 ATS.

49ers vs Seahawks Picks

About the Author
Ricky Henne writes for the Action Network's news team, covering all sports, events and breaking news. He also contributes to Action's NFL coverage. Ricky joined Action in 2022 with more than 20 years of experience covering professional sports. He wrote for the Los Angeles Chargers, New York Knicks and New York Rangers before entering the sports betting industry.

Follow Ricky Henne @rickyhenne on Twitter/X.

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