The Arizona Cardinals (2-3) and Green Bay Packers (3-2) will kick off the NFL Week 6 Sunday afternoon slate. Kickoff is set for 1 p.m. ET from Lambeau Field in Green Bay, Wis., on FOX. The game can be streamed on YouTube TV and other streaming services.
The Packers are 5-point favorites over the Cardinals (Packers -5) after the spread opened at the same number before the season. The game total is 49.5 after opening at 46.5. Green Bay is -250 to win outright on the moneyline, while Arizona is +190 to pull off the upset.
Arizona won 24-23 over the 49ers last week. Kyler Murray has seven touchdowns and two interceptions this season, while James Conner is averaging 75.8 rushing yards per game. The Packers won 24-19 over the Rams. Jordan Love threw for 224 yards and two touchdowns, both of which were thrown to Tucker Kraft, while Josh Jacobs ran for 73 yards and a touchdown.
Let's get into my Cardinals vs. Packers prediction and my NFL picks and predictions for Week 6.
Cardinals vs. Packers Odds, Pick, Prediction
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+5 -110 | 49.5 -110 / -110 | +190 |
| Packers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-5 -110 | 49.5 -110 / -110 | -250 |
- Cardinals vs. Packers spread: Packers -5
- Cardinals vs. Packers over/under: 49.5 points
- Cardinals vs. Packers moneyline: Packers -250, Cardinals +190
- Cardinals vs. Packers pick:Under 47
Our Packers vs. Cardinals best bet is on the under. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.
Spread
We have no bet on either side of the spread here. Green Bay is laying five points, but Arizona has proven it can be a spoiler on the road this season with covers against the Bills and 49ers.
Moneyline
Likewise, we have no pick on the moneyline.
Over/Under
One of our PRO systems has a signal on the under for this game.
My pick: Under 47
Arizona Cardinals vs. Green Bay Packers NFL Week 6 Preview
By Matt Trebby
The Cardinals started the season looking like they might be this season's underdog betting darlings. They covered in Week 1 as 6.5-point underdogs in Buffalo before winning by 31 points over the Rams in Week 2 as one-point favorites.
Arizona then lost two straight at home, both straight-up and against the spread (ATS), against the Lions and Commanders. The Cardinals bounced back with a comeback win over San Francisco, improving to 2-0 ATS on the road. Their games are 3-2 to the over this season, as well.
The Packers are 3-2 both ATS and to the over this season, although two of those covers came with Jordan Love out. Green Bay's QB1 got his first cover when the defense held onto a five-point win last week against the Rams.
Green Bay gets two straight home games in Weeks 6 and 7 after playing three on the road to start the season, including one down in Sao Paulo, Brazil.
By PJ Walsh
The Cardinals vs. Packers total is currently offering the third-largest betting model edge, according to Action PRO’s NFL Projections for Week 6.
While this total is listed at 47.5, Action PRO’s betting model projects this line at 49, which translates to a 2.3% edge for those interested in locking in the over.
Interestingly, while the consensus total has pushed to 47.5, a handful of sportsbooks, like DraftKings, are still at 47, providing what is essentially a free half-point of value for an important number in over/under betting, as well.
Pick: Under 47
Betting Trends
- 62% of bets and 64% of the money are on the Cardinals to cover the spread.
- 73% of bets and 67% of the money are on the over.
- 77% of bets and 41% of the money on the moneyline are on the Packers.
How to Watch: Time, Channel, Streaming
| Location: | Lambeau Field |
| Date: | Sunday, Oct. 13 |
| Kickoff Time: | 1 p.m. ET |
| TV / Streaming: | FOX / YouTube TV |
Packers vs. Cardinals is scheduled for a 1 p.m. ET start time, live from Lambeau Field in Green Bay, Wis., on Sunday, Oct. 13. The game is broadcast live by FOX and is streaming on YouTube TV.
NFL Weather
