All eyes will be on Detroit as the Lions host the Bills on Sunday. This is certainly the most intriguing NFL game on the Week 15 slate, so we've dug into some NFL prop picks.
Our betting experts have looked over the Bills vs. Lions props and found value on Jameson Williams and David Montgomery NFL picks.
Bills vs. Lions Player Props
In the table below, you'll find our NFL staff's top player prop picks for Bills vs. Lions. Click on any pick or team logo to navigate to a specific bet discussed in this article.
| Time (ET) | Prop |
|---|---|
| 4:25 p.m. | |
| 4:25 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | |
Bills vs. Lions
Jameson Williams
Anytime Touchdown (+240)
This could be the game of the year. It has a 54.5 implied total and a 2.5-point spread, so I expect a lot of touchdowns to be scored.
Jameson Williams is having a good season and when he gets the volume, he's been great. The Bills have been a good defense this season, but they just gave up 44 points to the Rams last week, and we could see a similar game here. The Bills have been one of the worst teams in the league at defending WR2s, ranking 29th according to DVOA, and they got absolutely crushed by Puka Nacua and Cooper Kupp last week.
Williams doesn't get a ton of red-zone work, but he's one of the best deep threats in the NFL. He has a much better chance to score than the +240 price indicates.
Pick: Jameson Williams Anytime Touchdown (+240)
Bills vs. Lions
David Montgomery
Over 2.5 Receptions (+130)
Jahmyr Gibbs has typically been the pass-catching option in this backfield, but he's been sharing the role equally with David Montgomery recently.
Both backs have 14 targets over their past four games and Montgomery has caught all of his targets in that stretch. In fact, he's brought in 32-of-34 targets this season.
Buffalo is one of the best matchups for running backs in the receiving game. The Bills have allowed the most targets, the second-most receptions and the third-most receiving yards to the position this season.
Montgomery has three-or-more receptions in four straight games and in six of his past eight games. I like him to extend that streak here, especially at plus money.
Pick: David Montgomery Over 2.5 Receptions (+130)
