Colts vs. Cardinals Odds
| Colts Odds | +2.5 (-115) |
| Cardinals Odds | -2.5 (-105) |
| Over/Under | 49 |
| Time | 8:20 p.m. ET |
| TV | CBS |
Even though Christmas is usually a day reserved for the NBA, this year, it falls on a Saturday and the NFL has decided to take advantage.
The Cleveland Browns play a pivotal game at the Green Bay Packers during the afternoon slot while the Indianapolis Colts face the Arizona Cardinals for the night cap.
Both the Colts and Cardinals will have important players out for this contest. Starting All-Pro left guard Quenton Nelson will miss this game on the COVID-19 list for the Colts, while All-Pro wide receiver DeAndre Hopkins will be out for this game and the rest of the regular season for the Cardinals.
The Cardinals have been reeling on the backs of Kyler Murray's poor play and have lost their last two, including an embarrassing 30-12 loss to the Detroit Lions, the league's worst team.
Meanwhile, the Colts have won six of their last eight contests on the backs of Jonathan Taylor, the best running back in the NFL this season. Indy ranks No. 1 in rushing on account of Taylor and that offensive line.
As a result of this current form, the public is hammering the Colts at plus money. The Colts' moneyline at +110 has over 78% of the total. The Colts' spread at +2.5 has roughly 96% of the money, too.
Read further to see whether the sharps and experts are fading or following the public for this important Christmas Day affair.
