Colts vs. Patriots Odds: Opening Week 10 Spread, Total

Colts vs Patriots Odds

Sunday, Nov. 12

9:30 a.m. ET

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Colts Odds
Spread	Total	Moneyline
-1.5 -110	43.5 -110o / -110u	-125

Patriots Odds
Spread	Total	Moneyline
+1.5 -110	43.5 -110o / -110u	+105

Odds via bet365. Get up-to-the-minute NFL odds here.

Indianapolis Colts

Minshew vs Jones doesn’t quite have the same ring as Manning vs Brady did for so many years in what used to be appointment viewing.

The Colts hit the road for the second straight week after beating the Panthers 27-13. They'll face an AFC opponent for the first time in three weeks when they visit New England. They're 3-2 straight up and 4-1 against the spread against their conference.

Meanwhile, the Colts are 3-1 both straight up and ATS on the road this year.

New England Patriots

The Patriots look for only their second win in six home games Sunday against Indianapolis. They fell in Washington 20-17 after Mac Jones threw a late pick. It was his ninth interception of the year for the much maligned quarterback, which is tied for most in the league.

New England is 2-7 ATS over its last six games, with the two covers coming against AFC East opponents. Meanwhile, the under’s hit regularly for them this season, going 6-3, although it’s 2-3 at Gillette Stadium.

Colts vs. Patriots

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