The Los Angeles Chargers (8-4) and Kansas City Chiefs (11-1) will face off on NFL Sunday Night Football. Kickoff is set for in 8:20 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City. The game will be broadcast live on NBC and Peacock.
Chargers vs Chiefs odds (via BetMGM) have the Chiefs as -250 moneyline favorites and the Chargers as +200 underdogs. The over/under is 43 total points (-110o / -110u). The Chiefs are 4.5-point favorites on the spread over the Chargers (-4.5).
Let's get into my Chargers vs Chiefs predictions and Sunday Night Football picks — plus the latest NFL betting trends, inactives (notably Ladd McConkey for Los Angeles) and weather forecast.
Chargers vs Chiefs Picks
Against the Spread
Finally, a good spot to back the Chiefs against the spread.
I'm taking them at -4 over a banged-up Chargers team that's quite fortunate to have the record they do.
Moneyline
I see no value on the Chiefs moneyline at -218.
Over/Under
I'm also passing on the game total, which sits at 42.5 or 43 depending on the sportsbook.
My Pick: Chiefs -4
Chargers vs Chiefs Odds, Prediction, Spread, Over/Under
| Chargers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4.5 -110 | 43 -110o / -110u | +200 |
| Chiefs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4.5 -110 | 43 -110o / -110u | -250 |
- Chargers vs. Chiefs spread: Chargers +4.5 (-110), Chiefs -4.5 (-110)
- Chargers vs. Chiefs over/under: 43 (-110o / -110u)
- Chargers vs. Chiefs moneyline: Chargers +200, Chiefs -250
- Chargers vs. Chiefs best bet: Chiefs -4
My Chargers vs. Chiefs best bet is on the Chiefs -4; the line has since moved to Chiefs -4.5 as of 7 p.m. ET on Sunday. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.
Chargers vs Chiefs Sunday Night Football Preview, Prediction
I can’t believe I’m about to say this, but I think there’s finally value on the Chiefs and we’ve hit the bottom of the market on them.
The Chiefs are 11-1, but 4-7 against the spread (ATS) this season, and they haven’t covered in six straight games — five of which they won. They infamously cannot cover as a big favorite either.
This is a really good spot for a number of reasons.
First, this is a tough situational spot for the Chargers, who traveled across the country last week to play the Falcons, returned home to L.A. and then traveled again to Kansas City. That’s a lot of travel and a lot of time zones covered.
The Chargers won and covered last week, but it was not an impressive performance.
Ladd McConkey accounted for 117 of Justin Herbert’s 147 passing yards, and the Chargers were outgained by the Falcons 350-187. Los Angeles sat back and let Kirk Cousins throw the ball, and it somehow worked.
That was not a performance the Chargers should be proud of, win aside.
This is a real test for Los Angeles against a Chiefs team coming off extended rest. The Chargers could make the AFC West interesting down the stretch with a win.
Who have the Chargers really beaten this year, though?
They have one win against a team over .500, and that’s the Broncos. Based on our NFL Luck Rankings, Los Angeles is right up there with Kansas City – and that’s saying something given how the Chiefs have won games this season.
The Chargers’ win over the Falcons was the luckiest of any team in the NFL over the last three seasons in terms of postgame win expectancy. Combine that with one of the easiest schedules in the NFL so far, and I’m looking to fade the Chargers.
Offensively, the Chiefs are looking like they’re starting to trend up.
Isiah Pacheco is back, which is a big boost, and DeAndre Hopkins has helped Patrick Mahomes. Since acquiring Hopkins, Mahomes has 13 touchdowns to three interceptions in six games, with a 69% completion percentage. That’s much more like the quarterback we’re used to.
Also, I expect D.J. Humphries to start at left tackle, which is massive. That position on the Chiefs' offensive line has been horrendous this season, which is why Mahomes’ pressure-to-sack ratio has skyrocketed.
Reports have been good on Humphreys, so I’m encouraged by that development.
Finally, I’m not sure how the Chargers are going to move the ball. Gus Edwards is a huge downgrade from J.K. Dobbins, and the passing game is a one-man show with McConkey.
My Pick: Chiefs -4
Chargers vs Chiefs Betting Trends
- 84% of bets and 79% of the money are on the Chiefs moneyline
- 83% of bets and 80% of the money are on the over
- 58% of bets and 60% of the money are on the Chargers to cover the spread
Chargers Trends
- Chargers are 4-1 in their last 5 games against the spread
- Chargers are 4-2 in their road games against the spread
- The totals have gone OVER in 3 of Chargers' last 5 games
Chiefs Trends
- Chiefs are 1-4 in their last 5 games against the spread
- The totals have gone OVER in 3 of Chiefs' last 5 games
- The totals have gone OVER in 3 of Chiefs' 6 last games at home
- Patrick Mahomes is 0-3-1 ATS vs. the AFC West this season and 4-10-1 ATS over the last three seasons vs. his division
Chargers vs Chiefs Inactives, Injuries
Chargers Inactives
- WR Ladd McConkey
- LB Denzel Perryman
- QB Easton Stick (emergency 3rd QB)
- S Tony Jefferson
- OL Brenden Jaimes
- OL Jordan McFadden
- DL Justin Eboigbe
Chiefs Inactives
- RB Clyde Edwards-Helaire
- DE Josh Uche
- OL C.J. Hanson
- T Ethan Driskell
- T Kingsley Suamataia
- DT Marlon Tuipulotu
- DE Malik Herring
