New York Giants at Seattle Seahawks Predictions, Odds, Preview: NFL Picks Week 5

New York Giants at Seattle Seahawks Predictions, Odds, Preview: NFL Picks Week 5 article feature image
Credit:

Action Network/Getty Images. Pictured: Daniel Jones (left) and Geno Smith.

The New York Giants (1-3) and Seattle Seahawks (3-1) will kick off the late Sunday afternoon slate of NFL Week 5. Kickoff is set for 4:25 p.m. ET from Lumen Field in Seattle on FOX, and the game can be streamed on YouTube TV and other streaming platforms.

The Seahawks are consensus 6.5-point favorites over the Giants (Seahawks -6.5) after the spread opened at Seahawks -3.5 before the season. The over/under is 43.5 after opening at 43. The Seahawks are -275 to win outright, while the Giants are +220 to pull off the upset.

The Giants lost 20-15 last week on Thursday night to the Cowboys. Daniel Jones has 4 touchdowns and 3 interceptions in 3 games this season, and he's averaging just 6.1 yards per pass attempt. The Seahawks suffered their first loss of the season last week, falling 42-29 to the Lions. Geno Smith has 4 touchdowns and 4 interceptions through 4 games, while Kenneth Walker has 4 touchdowns in just 2 games after scoring 3 times last week in Detroit.

Let's get into my Giants vs. Seahawks prediction and my NFL picks and predictions for Week 5.

Giants vs. Seahawks Odds, Pick, Prediction

Giants Logo
Sunday, Oct. 6
4:25 p.m. ET
FOX
Seahawks Logo
Giants Odds
SpreadTotalMoneyline
+6.5
-110
43.5
-110 / -110
+220
Seahawks Odds
SpreadTotalMoneyline
-6.5
-110
43.5
-110 / -110
-275
Odds via BetMGM. Get up-to-the-minute NFL odds here.
BetMGM Logo
  • Giants vs. Seahawks spread: Seahawks -6.5
  • Giants vs. Seahawks over/under: 43.5 points
  • Giants vs. Seahawks moneyline: Seahawks -275, Giants +220
  • Giants vs. Seahawks pick: Giants +6.5

My Seahawks vs. Giants best bet is on New York. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.

Spread

Our PRO systems and betting trends point toward taking the points with the Giants in Week 5.

Moneyline

We're not betting either moneyline for this game.

Over/Under

Our projections are in line with the total for this game.

My pick: Giants +6.5

New York Giants vs. Seattle Seahawks NFL Week 5 Preview

There are some decent patterns pointing toward taking the Giants plus the points, despite the Seahawks being the hot, early read in our PRO systems (Seattle’s attracting sharp action and big money in our database).

This could absolutely be a horrific take but there’s a chance that by the end of this season, the Giants and Seahawks are closer in team performance than the public currently thinks. The reason is there’s still a good chance the Giants vs. Seahawks game is being looked at by the public through a lens of last season, too.

The spread and total are right in range to activate the “Road Dog, Low Total After Bad Season” PRO System.

When the total isn't too high, small underdogs cover the spread 57% of the time in the first six weeks if they won six or fewer games the previous season — like the Giants. Basically, we have about one more week after this slate in which public biases perhaps have influenced the betting markets.

As a Michigan fan, I stan for Mike MacDonald. Seattle’s defense is also a microcosm of how I would draft a modern-day mock for every team that wants rangy playmakers. Entering Week 5, Seattle is holding opponents to 4.7 yards per play, the fourth-best mark in the NFL

But I also can’t help but notice they’ve played three offenses (Patriots, Broncos and the Skyler Thompson-led Dolphins) that will likely be rated among the bottom-seven units in the NFL by the end of the season. In the Seahawks' other game this season, they were blown to smithereens by the Lions.

According to our researcher Evan Abrams, Seahawks QB Geno Smith is 11-16-2 against the spread (ATS) as a favorite in his career and 22-18-2 as an underdog.

Also, when the Giants are coming off a loss under Brian Daboll, they're 14-6 ATS in their next game, including 11-5 ATS when listed as a underdog and 9-2 ATS as an underdog of three points or more.

Pick: Giants +6.5

Betting Trends

  • 57% of bets and 80% of the money are on the Seahawks to cover the spread.
  • 85% of bets and 93% of the money are on the over.
  • 72% of bets and 68% of the money on the moneyline are on the Seahawks.

How to Watch: Time, Channel, Streaming

Location:Lumen Field
Date:Sunday, Oct. 6
Kickoff Time:4:25 p.m. ET
TV / Streaming:FOX / YouTube TV

Seahawks vs. Giants is scheduled for a 4:25 p.m. ET start time, live from Lumen Field in Seattle, Wash., on Sunday, Oct. 6. The game is broadcasted live by FOX and is streaming on YouTube TV.

NFL Weather

Get the latest coverage on NFL Weather.

About the Author
Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

Follow Alex Kolodziej @KolodziejAlex on Twitter/X.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.