The New York Jets (7-10 in 2023) begin the regular season against the San Francisco 49ers (12-5) on Monday Night Football tonight, with kickoff set for 8:15 p.m. ET from Levi's Stadium in Santa Clara, California. The first Monday Night Football game of the 2024 NFL season is live on ABC and ESPN and streaming on ESPN+, YouTube TV and other major streaming platforms.
The 49ers are now favored by 3.5 points (-3.5) over the Jets in the latest NFL odds for Monday night after reports came out that running back Christian McCaffrey would be inactive due to a calf injury. The 49ers had been -4 earlier on Monday, with the spread as high as 49ers -4.5 at some books.
The over/under has now dropped to 42 after the McCaffrey news. It had dropped a point to 43 from the opening line of 44 earlier in the day. The 49ers have moved down to -185 favorites on the moneyline, with New York quarterback Aaron Rodgers, Breece Hall and the rest of the Jets now +155 to win the game and pull off the upset.
Rodgers will return to action almost 12 months to the day he tore his Achilles last year — also on Monday Night Football. Rodgers is back with a potentially stacked Jets offense starring Hall and Garrett Wilson. They'll face off againsta 49ers offense featuring Brock Purdy and the newly extended Brandon Aiyuk but missing CMC.
It's time for my Jets vs. 49ers predictions and my NFL predictions and picks for Week 1 Monday Night Football.
New York Jets vs. San Francisco 49ers Odds, Spread, Over/Under
| Jets Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3.5 -110 | 42 -110o / -110u | +155 |
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3.5 -110 | 42 -110o / -110u | -185 |
- Jets vs. 49ers Point Spread: 49ers -3.5 | Jets +3.5
- Jets vs. 49ers Total: Over/Under 42
- Jets vs. 49ers Moneyline: 49ers -185 | Jets +155
Jets vs. 49ers Monday Night Football Picks
SPREAD
I'm not betting a side in 49ers vs. Jets, as my projected line is in line with the market. If you really want to bet the Lions vs. Rams spread, our staff has a spread pick in our Jets vs. 49ers Picks, Predictions, Props, Odds, Best Bets for Monday Night Football.
MONEYLINE
I'm not betting the moneyline for Monday night either.
TOTAL
Both defenses should have the edge in this game, so I bet under 43.5, with that number available at ESPN BET and a few other books currently, according to our NFL Odds page. This line has now come down to 42 with the McCaffrey inactive decision, however.
49ers vs. Jets Pick: Under 43.5
Monday Night Football Betting Trends
- 57% of bets and 51% of the money are on the Jets to cover the spread.
- 71% of bets but only 28% of the money are on the over.
- 89% of bets and 92% of the money on the moneyline are on the 49ers.
JETS INJURIES
No major injuries listed on the injury report.
49ERS INJURIES
- RB Christian McCaffrey is out with a calf injury.
- WR Ricky Pearsall is out with chest.
How To Watch Monday Night Football
| 49ers vs. Jets | Monday Night Football Week 1 |
| Start Time: | 8:15 p.m. ET |
| TVÂ /Â Streaming: | ESPN, ABC / ESPN+, YouTube TV |
| Location: | Levi's Stadium in Santa Clara, Calif. |
Week 1 of Monday Night Football is scheduled for 8:15 p.m. ET live from Levi's Stadium on Monday. The game is live on ABC, ESPN and ESPN+ and will be available on streaming platforms, such as YouTube TV.
NFL Week 1 Monday Night Football Preview
Defensively, both the Jets and 49ers have elite units that finished top four in DVOA last season. Offensively, both teams have significant question marks.
New York Jets
For the Jets, the question is how effective can Aaron Rodgers be returning from an Achilles injury at age 40? In Rodgers' last full season in 2022, he posted a 91.1 passer rating and a 41.3 QBR, both career lows since he became a starter in 2008.
Rodgers has also struggled at times agains the 49ers' defensive line. The last time he faced them was in the Jan. 22, 2022 Divisional Round game, and he took five sacks while passing for just 225 yards with no touchdowns.
San Francisco 49ers
The 49ers have questions of their own. While they were able to come to terms with left tackle Trent Williams and wide receiver Brandon Aiyuk at the 11th hour, Williams hasn't practiced with the team much, and Aiyuk will reportedly be on a pitch count.
Even if Williams is Williams, the rest of the 49ers' offensive line is shaky. Left guard Aaron Banks was limited in practice all week and is questionable with a finger injury. Right guard Dominick Puni is a third-round rookie making his first career start. Center Jake Brendel was strong as run blocker last season, but earned a pass-blocking grade of just 45.3 from PFF (30th of 36 qualified centers). The same is true for right tackle Colton McKivitz, whose 58.3 pass-blocking grade ranked 66th of 81 qualified tackles.
How to Make NFL Picks on Chris Raybon's Jets vs. 49ers Prediction
In addition to both defenses having the upper hand, both teams tend to play at an extremely slow pace.
According to FTN, the 49ers were last in seconds between snaps in 2023 (28.4), and Rodgers' Packers were dead last in 2022 (29.2).
Per our Action Labs data, Primetime unders are 155-105-3 (60%) over the past five seasons, covering by 1.6 points per game.
Jets vs. 49ers Pick: Under 43.5 (to 43)
49ers vs. Jets Weather Forecast
