Cardinals vs. Packers Odds, Picks, Predictions: How To Bet This Thursday Night Football Over/Under

Cardinals vs. Packers Odds, Picks, Predictions: How To Bet This Thursday Night Football Over/Under article feature image
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Getty Images. Pictured: Packers QB Aaron Rodgers, Cardinals QB Kyler Murray

  • In search of Cardinals vs. Packers odds? Find the spread and over/under in our expert's guide to betting Thursday Night Football below.
  • After a two-and-a-half-point adjustment to his projections, find out where our expert sees an edge on this total.

Cardinals vs. Packers Odds

Cardinals Odds-6.5
Packers Odds+6.5
Over/Under50
Time8:20 p.m. ET
TVFOX, NFL Network
Odds via DraftKings. Get up-to-the-minute NFL odds here.

The Cardinals opened as 3.5-point favorites, but after Packers wide receivers Davante Adams and Allen Lazard were ruled out and news broke that defense coordinator Joe Barry is also set to miss the game, the spread has jumped up to Cardinals -6.5.

The total, meanwhile, has dropped two full points from the opener — but there's still value in betting it (at the right price). Let's take a closer look.


Click the arrow to expand injury reports

Cardinals vs. Packers Injury Report

Packers Injuries

  • T Dennis Kelley (back): Doubtful
  • CB Kevin King (shoulder/back): Questionable
  • LB Preston Smith (oblique): Questionable

Cardinals Injuries

  • WR DeAndre Hopkins (hamstring): Questionable
  • TE Darnell Daniels (hamstring): Questionable
  • OL Max Garcia (Achilles): Questionable
  • DE J.J. Watt (shoulder): Out
  • DT Rashard Lawrence (calf): Questionable

Cardinals vs. Packers Matchup

Cardinals DefenseDVOA RankPackers Offense
2Total4
2Pass5
7Rush13
Cardinals OffenseDVOA RankPackers Defense
8Total24
4Pass21
24Rush23
Football Outsiders' DVOA measures efficiency by comparing a team's success on every play to the league average based on situation and opponent.

Packers Offense Takes A Blow Without Davante Adams

I lowered the Packers' team rating two full points because Davante Adams was ruled out.

Aaron Rodgers is a first-ballot Hall of Famer-caliber quarterback, and I'm sure he'll get the most out of Randall Cobb, Equanimeous St. Brown and Amari Rodgers. However, it's the worst possible time to lose his top target (33% of targets this season) as the Packers face the 7-0 Cardinals.

The offensive line will be without David Bakhtiari for one more week as he's expected to come off the IR for Week 9. They'll also be starting backup center Lucas Patrick for the second straight game as Josh Meyers remains out due to a knee injury.

Key Cardinals Injuries To Watch

Kyler Murray should have no issues moving the ball against the Packers' secondary that continues to be without shutdown corner Jaire Alexander. However, DeAndre Hopkins has yet to practice this week due to a hamstring injury. He's expected to play, but there's a chance he'll be playing at less than 100% on the short week.

I'll also be looking out for center Max Garcia's status — he's been filling in for the injured Rodney Hudson, so if Garcia is unable to suit up, it will be third-stringer Sean Harlow who starts.


Cardinals vs. Packers Picks

I projected this total at 50.5 points before the Adams news and lowered it to 48 based on the current injury report.

The Packers should struggle to put up points without their top WR against the second-ranked defense in DVOA. I figure they'll lean on Aaron Jones, A.J. Dillion and the running game more as a result, and if you couple that with their slow pace of play (29th), it sets up nicely for the under.

The Cardinals might not have to put up 30+ points to go 8-0 against a depleted Packers offense. As a result, the Cardinals could also opt for a more conservative run-heavy game plan, especially considering Hopkins may not be 100%.

Fifty is a key number for NFL totals, and I only expect it to fall, so it's critical to lock the under in while it's still 50.5 points.

Pick: Under 50.5
Best book as of writing:BetMGM

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About the Author
Sean is The Action Network's Director of Predictive Analytics. He was named the No. 1 fantasy football draft ranker of 2019 by FantasyPros, where he's also finished as the top in-season ranker in three of the past five seasons

Follow Sean Koerner @The_Oddsmaker on Twitter/X.

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