Week 2 NFL Odds, Spreads & Over/Unders: Your Guide To Betting All of Sunday’s Games

Action Network Staff

Updated:

Sep 19, 2021, 11:54 AM EDT

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Getty Images. Pictured: Vikings RB Dalvin Cook, Cowboys QB Dak Prescott, Seahawks WR D.K. Metcalf

NFL Odds: Spreads & Over/Unders

Game	Spread	Over/Under
Broncos at Jaguars	DEN -6	45.5
Texans at Browns	CLE -13	48
Bills at Dolphins	BUF -3.5	47.5
Rams at Colts	LAR -3.5	48.5
49ers at Eagles	SF -3	48.5
Bengals at Bears	CHI -2.5	45
Raiders at Steelers	PIT -6.5	46.5
Patriots at Jets	NE -6	43
Saints at Panthers	NO -3	44.5
Vikings at Cardinals	ARI -4	50.5
Falcons at Buccaneers	TB -12.5	51.5
Cowboys at Chargers	LAC -3	55
Titans at Seahawks	SEA -6.5	54
Odds via DraftKings. Check real-time NFL odds here.

NFL Picks For Every Week 2 Game

Click on a matchup to read that betting preview
Saints-Panthers	1 p.m. ET
Bengals-Bears	1 p.m. ET
Texans-Browns	1 p.m. ET
Rams-Colts	1 p.m. ET
Broncos-Jaguars	1 p.m. ET
Bills-Dolphins	1 p.m. ET
Patriots-Jets	1 p.m. ET
49ers-Eagles	1 p.m. ET
Raiders-Steelers	1 p.m. ET
Vikings-Cardinals	4:05 p.m. ET
Falcons-Buccaneers	4:05 p.m. ET
Cowboys-Chargers	4:25 p.m. ET
Titans-Seahawks	4:25 p.m. ET

Week 2 NFL Odds, Picks & Previews For Every Game Read now

Our Best NFL Bets For Week 2

Click on a pick to read about it
Panthers +3.5 vs. Saints
Eagles +3 vs. 49ers
Browns -12.5 vs. Texans
Rams first half -2.5 at Colts
Chargers -3 vs. Cowboys
Cowboys-Chargers Over 54.5

Our 5 Best NFL Bets For Sunday's Early Games Read now

Our 3 Favorite NFL Bets For Sunday's Late Games Read now

NFL Schedule For Week 2

Click on a matchup for more details
Game	Time
Broncos at Jaguars	1 p.m. ET
Texans at Browns	1 p.m. ET
Bills at Dolphins	1 p.m. ET
Rams at Colts	1 p.m. ET
49ers at Eagles	1 p.m. ET
Bengals at Bears	1 p.m. ET
Raiders at Steelers	1 p.m. ET
Patriots at Jets	1 p.m. ET
Saints at Panthers	1 p.m. ET
Vikings at Cardinals	4:05 p.m. ET
Falcons at Buccaneers	4:05 p.m. ET
Cowboys at Chargers	4:25 p.m. ET
Titans at Seahawks	4:25 p.m. ET

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