When it comes to early NFL picks, Week 6 has been much quieter than previous weeks on the sharp action front.
This doesn't mean that pros are laying off Week 6 entirely, just that there are fewer games attracting market-moving action thus far.
Interestingly, while our Action PRO premium betting tools are reporting a relatively quiet Sunday slate, it's Thursday Night Football and Monday Night Football already drawing early money from professional bettors.
Continue reading to see the NFL predictions that wise guys are already making for 49ers vs. Seahawks and Bills vs. Jets.
The 2 Sharpest Early NFL Picks Week 6
*Odds as of Tuesday afternoon
49ers vs. Seahawks Pick
Thursday, Oct. 10 | 8:15 p.m. ET | Amazon Prime Video
NFL Week 5 wasn't pretty for the 49ers and Seahawks.
As a 7-point favorite, San Francisco lost to Arizona, 24-23, while Seattle, which closed at -7 as well, fell to the New York Giants by nine points.
Looking ahead to Week 6, the 49ers are -3.5 against the Seahawks at most sportsbooks and the sharp side, to this point, is quite clear.
