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As NFL Preseason Week 3 rolls on, we're here once again with our best NFL preseason picks for today's eight-game slate. Week 3 on Saturday kicks off with five games in the 1 p.m. ET window, with a solo game at 4 p.m. ET, 7:30 p.m. ET and a nightcap at 10 p.m. ET.
Let's get into our NFL preseason best bets that our experts are betting on Saturday.
NFL Best Bets Today
The team logos in the table below represent each of the matchups that our NFL betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 4:00 p.m. | |
  | 10:00 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | ||
Sam Farley's Chargers vs Cowboys Preseason Pick: Bet Trey Lance to Lead Dallas
By Sam Farley
We have to back the Cowboys to cover the spread at home against the Chargers. The Chargers have been terrible in the preseason without Justin Herbert under center and have put up just 12 points across two games as Easton Stick and Luis Perez have yet to throw a touchdown pass.
The Cowboys will sit Dak Prescott and most likely limit Cooper Rush's time on the field, but that gives Trey Lance a real opportunity to make a statement and push to be Dallas' backup.
Lance has looked improved in camp and went 15-for-23 for 151 yards and a touchdown last week as he led the Cowboys to a win over the Raiders. He also threw for 188 yards in the week before that. This is Lance SZN.
Pick: Cowboys -3.5 (-110)
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John LanFranca's Browns vs Seahawks Preseason Pick: Back Seattle Early
Kevin Stefanski seems to want Deshaun Watson to play in Cleveland's preseason finale against the Seahawks, but also wouldn't entirely commit to it. Watson was held out of Wednesday's practice with general soreness before returning to work on Thursday. Regardless, injuries on the offensive line are creating depth issues as some of the key pieces up front have barely been involved in practice. As a result, I'd be shocked if Watson is in the game for very long on Saturday night.
However, we do know that Seattle's starting offense is going to play in this game. Geno Smith and company are set to make their preseason debut. If Smith has early success, that likely means the Seahawks have put points on the board. Sam Howell will take over the offense next and he led two scoring drives in Seattle's first preseason game, then proceeded to carve up the Titans to the tune of a 136.0 passer rating in Week 2.
Seattle's starting defense has only played two series during the exhibition season and forced two three-and-outs. They will also take the field against this banged up Browns' offensive line. I really like the chances of Seattle jumping out to an early lead.
Pick: Seahawks -0.5 1st Half (+105)
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NFL Preseason Odds for Week 3 Saturday
- Rams vs Texans: Texans -3.5
- Panthers vs Bills: Panthers -4.5
- Ravens vs Packers: Packers -2.5
- Steelers vs Lions: Steelers -7
- Vikings vs Eagles: Eagles -2.5
- Chargers vs Cowboys: Cowboys -3.5
- Giants vs Jets: Giants -2.5
- Browns vs Seahawks: Browns -1
