NFL Week 4 Predictions, Spread and Over/Under Picks

NFL Week 4 Predictions, Spread and Over/Under Picks article feature image
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Saquon Barkley #26 of the Philadelphia Eagles (Photo by Michael Owens/Getty Images)

We’re utilizing PRO Systems and sharp insights from PRO Report to find the best NFL Week 4 predictions. It's early in the betting market cycle, but here are some goodies to consider.

We’ve already tracked sharp action, big money, and top experts taking advantage of an over/under pick which is potentially off price. Additionally, another spread that fits a sweet situational angle.

Here are a couple of sharp picks for bettors in Week 4.


NFL Week 4 Predictions, Spread and Over/Under Picks

PRO Systems can build endless betting trends that are reliable for making informed decisions.

For Sunday's Week 4 card, one noteworthy PRO System banks on fading the public after a team plays poorly. Basically, there's a Week 4 spread nobody wants anything to do with — likely because of how the team performed this past week.

This system boasts an impressive record, having cashed 61% of spread predictions.

Last week, this PRO System nailed both of its picks: the Panthers and the Broncos against the spread, both of which won outright.


Eagles vs. Buccaneers Prediction for Week 4

Eagles Logo
Sunday, Sep 29
1 p.m. ET
FOX
Buccaneers Logo
Eagles Odds
SpreadTotalMoneyline
-2.5
-110
44.5
-115o / -105u
-142
Buccaneers Odds
SpreadTotalMoneyline
+2.5
-110
44.5
-115o / -105u
+120
Odds via FanDuel. Get up-to-the-minute NFL odds here.
FanDuel Logo

Let's start with the Eagles vs. Buccaneers game, teed up for a hot situational spot.

The Eagles are currently favored by -2.5 points. Neither team played particularly well last week, but there is a solid angle to exploit here, thanks to our PRO Systems.

In this matchup, the PRO System indicates a pick on the