Panthers vs Bears Picks, Odds, Predictions for NFL Week 5

Panthers vs Bears Picks, Odds, Predictions for NFL Week 5 article feature image
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Cole Kmet #85 of the Chicago Bears (Photo by Todd Kirkland/Getty Images)

Four of five PRO signals are aligned on the Panthers vs. Bearsspread, marking one of the strongest predictions for NFL Week 5.

In an intriguing Week 5 matchup, the Panthers travel to Chicago to face off against the Bears at Soldier Field. It's an early-window kick, set for 1 p.m. ET. The Panthers, both 1-3 straight up and against the spread and led by veteran quarterback Andy Dalton, are looking to bounce back.

Meanwhile, the Bears are anchored by rookie sensation and No. 1 overall draft pick, QB Caleb Williams, standing at an even 2-2 straight up with a 2-1-1 performance against the spread.

The spread is set at Bears -4, with a total of over/under of 41. As both teams look to gain momentum, the betting landscape presents some compelling angles.

Panthers vs. Bears Odds, Picks, Predictions

Panthers Logo
Sunday, Oct 6
1 p.m. ET
FOX
Bears Logo
Panthers Odds
SpreadTotalMoneyline
+4
-110
40.5
-114o / -107u
+165
Bears Odds
SpreadTotalMoneyline
-4
-110
40.5
-114o / -107u
-205
Odds via BetRivers. Get up-to-the-minute NFL odds here.
BetRivers Logo
  • Panthers vs. Bears spread: Bears -4
  • Panthers vs. Bears over/under: 40.5
  • Panthers vs. Bears moneyline: Panthers +165, Bears -205

Spread

The line has the Bears favored by 4 points, reflecting home-field advantage and perhaps the early promise of Caleb Williams’ storied potential. This spread sets the stage for a critical betting decision, where expert insights and systems will weigh heavily into which side bettors might settle on.

Over/Under

The total for this matchup is set at 41 points. Given the dynamics of both teams, this number presents a key decision point for bettors contemplating potential game scripts and outcomes. Both teams went over the total last weekend.

Moneyline

The moneyline odds position the Panthers as the underdogs at +165, while the Bears are favored at -205.

Player Prop

Checking our updated PRO Props Projections, Carolina RB Miles Sanders is +550 to score a touchdown. The price implies a a 15.4% chance.

PRO Projections predict Sanders to score 17% of the time. It's just a 1.6% edge, which falls short of our recommendation of 3.5%.

Panthers vs. Bears Prediction

Sorting the Week 5 spreads in PRO by strength, Panthers vs. Bears features premium PRO signals aligned.

Point Spread

Several expert and data-backed signals point towards the