Seattle Seahawks at Detroit Lions Predictions, Odds, Preview: NFL Monday Night Football Picks

Seattle Seahawks at Detroit Lions Predictions, Odds, Preview: NFL Monday Night Football Picks article feature image
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Action Network/Getty Images. Pictured: Geno Smith (left) and Jared Goff.

The Seattle Seahawks (3-0) and Detroit Lions (2-1) will face off on NFL Week 4's Monday Night Football. Kickoff is set for 8:15 p.m. ET from Ford Field in Detroit. The game will be broadcast live on ABC and can be streamed on platforms like ESPN+ and YouTube TV.

The Lions are 4.5-point favorites, with the consensus game total set at 47. The spread opened earlier this year at Lions -5.5, while the total was at 49. Detroit is a -225 favorite on the moneyline, while Seattle is +180 to pull off the upset.

The Seahawks are off to a great start, but face their first real test this week. Seattle has beaten the Broncos, Patriots and the Tua Tagovailoa-less Dolphins this season. The Lions bounced back last week with an exciting win over the Cardinals. Jared Goff completed 18-of-23 passes last week and threw touchdowns, but the Lions ran for 187 yards and held Kyler Murray in check.

Let's get into my Seahawks vs. Lions prediction and my NFL predictions for Monday Night Football.


Seahawks vs. Lions Odds, Picks, Prediction

Seahawks Logo
Monday, Sept. 30
8:15 p.m. ET
ABC
Lions Logo
Seahawks Odds
SpreadTotalMoneyline
+4.5
-110
46.5
-110 / -110
+180
Lions Odds
SpreadTotalMoneyline
-4.5
-110
46.5
-110 / -110
-225
Odds via BetMGM. Get up-to-the-minute NFL odds here.
BetMGM Logo

Seahawks vs. Lions spread: Lions -4.5
Seahawks vs. Lions over/under: 46.5 points
Seahawks vs. Lions moneyline: Lions -225 · Seahawks +180
Seahawks vs. Lions pick: Lions Team Total Under 25.5

My Seahawks vs. Lions best bet is on the Lions team total. I'm betting the Lions to score under 25.5 points. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.

Spread

I'm not going to bet the Seahawks vs. Lions spread.

Moneyline

I'm passing on the Seahawks vs. Lions moneyline.

Over/Under

The Seahawks vs. Lions over/under is a pass for me, but I'm betting another total in this game.

My Pick: Lions Team Total Under 25.5

Seattle Seahawks vs. Detroit Lions NFL Monday Night Football Preview

This isn't the first time the Seahawks and Lions have met in recent years, and you'll likely hear a lot about those recent meetings in the buildup to this game.

Seattle won 37-31 in overtime last season, 48-45 the year before and 51-29 the season before that — with offense and fireworks for days and at least 41 points in the second half of all three games. That would certainly lean toward an over here, but I'm actually looking at a different game from last season: Detroit's 38-6 drubbing at the hands of Mike Macdonald's Ravens.

Jared Goff still doesn't handle pressure well and is going to see plenty of it against Macdonald's Seattle defense. The Seahawks have been incredible on defense, ranking top three in DVOA against both the run and the pass. Macdonald has totally turned this unit around and his unique defensive play calling has been especially good against the league's best offensive systems.

Additionally, Detroit's offense actually hasn't been that great so far this season. The passing attack ranks below average and the unit as a whole is just 13th by DVOA, a far cry from expectations for Ben Johnson's unit.

And now things may be much worse with star center Frank Ragnow sidelined. Per Nate Tice, the Lions with Ragnow last season ranked top four in yards per play, success rate and EPA per play. With Ragnow out, they plummeted to the bottom six in both success rate and EPA per play. For a team built entirely around winning in the trenches, Ragnow has proven to be key to Detroit's success.

I'm not sure books have caught up to how good Seattle's defense is — nor to Detroit's relatively tepid offensive output thus far.

The Lions have only gone over 25.5 points once — by just half a point — and needed an overtime touchdown to get there in Week 1. Detroit has scored 20, 16 and 20 in regulation, and that was against the Rams, Bucs and Cardinals, all below average defenses, with two of them among the worst in the league.

This is a great clash between outstanding NFC teams, the sort of cagey battle that could very well end up being a playoff preview. Let's see what Seattle's remade defense can do against this high-charged Lions offense.

Pick: Lions Team Total Under 25.5


Betting Trends

  • 54% of bets and 46% of the money are on the Seahawks to cover the spread.
  • 41% of bets and 36% of the money are on the over.

How to Watch: Time, Channel, Streaming

Location:Ford Field
Date:Monday, Sept. 30
Kickoff Time:8:15 p.m. ET
TV / Streaming:ABC / ESPN+ and YouTube TV

Seahawks vs. Lions is scheduled for a 8:15 p.m. ET start time, live from Ford Field in Detroit, MI, on Monday night. The game is broadcasted live by ABC and is streaming on ESPN+ and YouTube TV.

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About the Author
Brandon Anderson is a staff writer at the Action Network, specializing in NFL and NBA coverage. He provides weekly NFL power rankings and picks for every game, as well as contributing to NBA analysis, regularly appearing on the BUCKETS Podcast. With a deep background in sports betting and fantasy football, Brandon is known for spotting long-shot futures and writing for various outlets like Sports Illustrated, BetMGM, and more before joining the Action Network.

Follow Brandon Anderson @wheatonbrando on Twitter/X.

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