NFC West rivals, the Seattle Seahawks (4-5-0) and San Francisco 49ers (5-4-0), meet in NFL Week 11. Kickoff is set for in 4:05 p.m. ET from Levi's Stadium in Santa Clara, Calif. The game will be broadcast live on FOX.
The 49ers are favored by 6 points over the Seahawks (49ers -6) with the game total set at 49 (-110/-110). The 49ers are -265 moneyline favorites to win outright, while the Seahawks are +215 underdogs.
The Seahawks are coming off their bye week and will hope Geno Smith has DK Metcalf to throw to after Seattle’s WR1 missed the last two games. The 49ers beat the Buccaneers last week on a last-second field goal. Brock Purdy threw for 353 yards and two touchdowns, while Christian McCaffrey had 107 yards of total offense in his season debut.
Let's get into my 49ers vs Seahawks predictions and NFL picks.
Seahawks vs 49ers Expert Picks
Spread
The Seahawks are entering a must-win game against a 49ers team that hasn't been its vintage self this season. I'm going to take the points and back Seattle. I'm hoping we get seven points, but I am content playing +6.5.
Moneyline
I'm backing Seattle, but I'm doing so by taking the points. I'm not betting the Seahawks to win outright on the moneyline.
Over/Under
I have no pick on this game's total.
My Pick: Seahawks +6.5 (-110)
Seahawks vs 49ers Odds, Prediction, Spread, Over/Under
| Seahawks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6 -110 | 49 -110o / -110u | +215 |
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6 -110 | 49 -110o / -110u | -265 |
- Seahawks vs. 49ers spread: Seahawks +6 (-110), 49ers -6 (-110)
- Seahawks vs. 49ers over/under: 49 (-110o / -110u)
- Seahawks vs. 49ers moneyline: Seahawks +215, 49ers -265
- Seahawks vs. 49ers prediction: Seahawks +6.5 (-110)
MySeahawks vs. 49ers best bet is on Seattle. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.
Seahawks vs 49ers Preview: Buy Low on Seattle?
I’m taking a leap of faith here.
There’s obviously an element of fading the 49ers that scares me. They’ve been dominant on the box score, but it hasn’t been reflective on the scoreboard. The 49ers have gone from the best team in the NFL last year in the red zone to the worst this season.
That means there’s some positive regression coming their way.
Simply put, I can’t get to this number. Home-field advantage hasn’t been that important this season, especially when you talk about divisional games.
In these teams’ first matchup of the season in Seattle, the Seahawks were without Tariq Woolen and playing on a second straight short week. There were issues on the offensive line, specifically at right tackle, as well.
This is a much better spot for the Seahawks and we’re getting three more points than we did earlier this season.
This is a spot for an all-in, all-out effort from the Seahawks coming off their bye week.
Seattle’s most likely path to the playoffs will come through winning the NFC West. It won’t be able to do that having lost to the Rams earlier this season and twice to the 49ers. Also, the Seahawks will be getting the 49ers after a cross-country nail-biter against the Buccaneers.
I’m high on Seahawks head coach Mike Macdonald and trust he’ll have a strong game plan coming off a bye. It will help that they’ll be more healthy.
Speaking of a strong game plan, it will be easier for the Seahawks to do that offensively with DK Metcalf back in the fold. He’s missed the past couple of games for the Seahawks but leads the NFL in deep targets. He opens up this offense for guys like Tyler Lockett and Jaxon Smith-Njigba underneath.
If Metcalf doesn’t play, I’ll want Seahawks +7. Regardless, though, this is a great spot to back Seattle.
My Pick: Seahawks +6.5 (-110)
Seahawks vs 49ers Betting Trends
Seahawks Trends
- The totals have gone OVER in 3 of Seahawks' last 5 games
- Seahawks are 1-1 in their road games against the spread
- Seahawks are 0-4 in their last 5 games against the spread
49ers Trends
- The totals have gone OVER in 3 of 49ers' 5 last games at home
- 49ers are 2-3 in their last 5 games against the spread
