Two powerhouses meet for Sunday Night Football this weekend.
Surprisingly, the most interesting betting patterns tracked ahead of 49ers vs. Bills in Week 13 isn't which team will win — or even cover — but rather how many total points will be scored.
The latest update in PRO Report displays respected bettors and big money both aligned on the 49ers vs. Bills over/under, suggesting one of the stronger prime-time picks for Sunday Night Football.
Both offenses are loaded with star power entering Week 13 primetime. Josh Allen and the Bills are the No. 3 scoring team in the NFL, while the 49ers average the second-most yards per play.
Two of five PRO signals agreeing on the over/under of 44.5 suggests a sharp prediction for Sunday Night Football.
Sunday Night Football Pick: 49ers vs. Bills Over/Under Prediction
The 49ers are 6-5 to the over, while a potent Bills offense behind Allen, an MVP candidate, is 7-3.
Scanning the Highmark Stadium forecast and 49ers vs. Bills weather report reveals winds shouldn't be an issue on Sunday Night Football.
However,