San Francisco 49ers running back Christian McCaffrey has become the odds-on favorite to win Offensive Player of the Year.
McCaffrey was one of the favorites heading into Week 4 — along with Tyreek Hill — but after his performance Sunday's performance against the Cardinals, he's now the clear favorite.
McCaffrey ran for 106 yards and three touchdowns on the ground while also catching seven passes for 71 yards and another score.
The Stanford product is now +210 to win OPOY after opening at +1400 at BetMGM. McCaffrey is the biggest liability at BetMGM and accounts for the most tickets and handle.
Hill is still not far behind at +550, but the Dolphins receiver recorded only three catches for 58 yards against the Bills this past week.
Justin Jefferson has also been creeping up the odds board. He's also +550 to win OPOY after snagging three touchdowns in his last two games.
It's important to note that quarterbacks are eligible to win Offensive Player of the Year, but the award typically goes to non-quarterbacks due to signal-callers winning MVP most years.
Offensive Player of the Year Odds
Odds according to BetMGM as of October 3.
| Player | Odds |
|---|---|
| Christian McCaffrey | +210 |
| Justin Jefferson | +550 |
| Tyreek Hill | +550 |
| Lamar Jackson | +2000 |
| Stefon Diggs | +2000 |
| Jalen Hurts | +2800 |
| CeeDee Lamb | +2800 |
| Davante Adams | +3000 |
| Amon-Ra St. Brown | +3000 |
| Josh Allen | +3500 |
| Tua Tagovailoa | +3500 |
| Keenan Allen | +3500 |
| Patrick Mahomes | +4000 |
| A.J. Brown | +4000 |
| Tony Pollard | +4000 |
| Ja'Marr Chase | +5000 |
| Justin Herbert | +5000 |
| Deebo Samuel | +5000 |
| Travis Kelce | +5000 |
| Derrick Henry | +5000 |
| Bijan Robinson | +5000 |
| D'Andre Swift | +5000 |
| Chris Olave | +6600 |
| Brandon Aiyuk | +6600 |
| Anthony Richardson | +6600 |
| Breece Hall | +8000 |
| Jaylen Waddle | +8000 |
| D.K. Metcalf | +8000 |
| Brock Purdy | +8000 |
| Garrett Wilson | +10000 |
| Trevor Lawrence | +10000 |
| Josh Jacobs | +10000 |
| DeAndre Hopkins | +10000 |
| Travis Etienne Jr. | +10000 |
| Austin Ekeler | +10000 |
| Dak Prescott | +10000 |
| Kenneth Walker III | +10000 |
| Devonta Smith | +10000 |
| Calvin Ridley | +10000 |
| Isiah Pacheco | +10000 |
| Jared Goff | +10000 |
| David Montgomery | +10000 |
| Joe Burrow | +12500 |
| Mike Evans | +12500 |
| Kirk Cousins | +12500 |
| Gabriel Davis | +12500 |
| Cooper Kupp | +15000 |
| Jonathan Taylor | +15000 |
| Justin Fields | +15000 |
| Saquon Barkley | +15000 |
| Jahmyr Gibbs | +15000 |
| Geno Smith | +15000 |
| Tyler Lockett | +15000 |
| Courtland Sutton | +15000 |
| Brian Robinson Jr. | +15000 |
| T.J. Hockenson | +15000 |
| Raheem Mostert | +15000 |
| Sam Howell | +15000 |
| Nico Collins | +15000 |
| James Cook | +15000 |
| Deshaun Watson | +15000 |
| Zay Flowers | +15000 |
| Matthew Stafford | +20000 |
| Javonte Williams | +20000 |
| Daniel Jones | +20000 |
| Russell Wilson | +20000 |
| Terry McLaurin | +20000 |
| George Kittle | +20000 |
| Dameon Pierce | +20000 |
| Amari Cooper | +20000 |
| D.J. Moore | +20000 |
| Jerry Jeudy | +20000 |
| Alvin Kamara | +20000 |
| Kyle Pitts | +20000 |
| Chris Godwin | +20000 |
| Joe Mixon | +20000 |
| George Pickens | +20000 |
| Drake London | +20000 |
| Jahan Dotson | +20000 |
| Mark Andrews | +20000 |
| Christian Kirk | +20000 |
| Michael Thomas | +20000 |
| Najee Harris | +20000 |
| David Njoku | +20000 |
| Marquise Brown | +20000 |
| Rhamondre Stevenson | +25000 |
| Aaron Jones | +25000 |
| Kyler Murray | +25000 |
| Darren Waller | +25000 |
| Derek Carr | +25000 |
| Rachaad White | +25000 |
| Miles Sanders | +25000 |
| Rashod Bateman | +25000 |
| Khalil Herbert | +25000 |
| Evan Engram | +25000 |
| Treylon Burks | +25000 |
| Jordan Addison | +25000 |
| Mac Jones | +25000 |
| Kadarius Toney | +25000 |
| Dallas Goedert | +25000 |
| Romeo Doubs | +25000 |
| James Conner | +25000 |
| Bryce Young | +25000 |
| Elijah Moore | +25000 |
| Ryan Tannehill | +25000 |
| Desmond Ridder | +25000 |
