NFL Predictions, Odds for Every Game: Week 2 NFL Schedule

Action Network Staff

Updated:

Sep 15, 2024, 12:55 PM EDT

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NFL Predictions, Odds for Every Game: Week 2 NFL Schedule article feature image

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Getty Images. Pictured: An NFL football during the 2024 season.

Our experts have taken a look up and down the NFL Week 2 schedule, and they've come away with their best bets for every game.

The tightest spread at the moment is in Rams vs. Cardinals, where the Cardinals are currently just 1-point favorites (-1). The biggest spread is in Raiders vs. Ravens, as Baltimore is an 8.5-point favorite (-8.5) against Las Vegas. The highest over/under is in Bucs vs. Lions at 51.5 points, and the lowest total is the over/under 36.5 in Steelers vs. Broncos.

But those are just the superlatives. Let's get to the Week 2 NFL odds, our expert picks, and NFL predictions for every game.

Week 2 NFL Predictions

Chargers vs. Panthers Prediction: Panthers to cover the spread
Saints vs. Cowboys Prediction: Cowboys to cover -19.5 alt spread
Raiders vs. Ravens Prediction: Ravens to cover the spread
Bucs vs. Lions Prediction: Under
Jets vs. Titans Prediction: Titans to cover the spread
Seahawks vs. Patriots Prediction: Under
Browns vs. Jaguars Prediction: Browns to cover the spread
49ers vs. Vikings Prediction: 49ers to cover the spread
Colts vs. Packers Prediction: Packers to cover the spread
Giants vs. Commanders Prediction: Giants moneyline
Rams vs. Cardinals Prediction: Rams to cover the spread
Bengals vs. Chiefs Prediction: Bengals to cover the spread
Steelers vs. Broncos Prediction: Broncos to cover the spread
Bears vs. Texans Prediction: Under
Falcons vs. Eagles Prediction: Under

NFL Odds for Week 2

Chargers vs. Panthers Spread: Chargers -5
Saints vs. Cowboys Spread: Cowboys -6
Raiders vs. Ravens Spread: Ravens -8.5
Bucs vs. Lions Spread: Lions -7.5
Jets vs. Titans Spread: Jets -4
Seahawks vs. Patriots Spread: Seahawks -3
Browns vs. Jaguars Spread: Jaguars -3
49ers vs. Vikings Spread: 49ers -4.5
Colts vs. Packers Spread: Colts -2.5
Giants vs. Commanders Spread: Commanders -1.5
Rams vs. Cardinals Spread: Cardinals -1
Bengals vs. Chiefs Spread: Chiefs -6.5
Steelers vs. Broncos Spread: Steelers -2.5
Sunday Night Football Bears vs. Texans Spread: Texans -6
Monday Night Football Falcons vs. Eagles Spread: Eagles -6

Week 2 NFL Schedule

Los Angeles Chargers at Carolina Panthers

Sunday, Sep 15

1 p.m. ET

CBS

Chargers Odds
Spread	Total	Moneyline
-5 -110	38.5 -110o / -110u	-240

Panthers Odds
Spread	Total	Moneyline
+5 -110	38.5 -110o / -110u	+195

Odds via bet365. Get up-to-the-minute NFL odds here.

Chargers vs. Panthers Spread: Chargers -5
Chargers vs. Panthers Over/Under: 38.5 points
Chargers vs. Panthers Moneyline: Chargers -240, Panthers +195
Chargers vs. Panthers Pick, Prediction: Panthers to cover the spread

New Orleans Saints at Dallas Cowboys

Sunday, Sep 15

1 p.m. ET

FOX

Saints Odds
Spread	Total	Moneyline
+6 -105	47 -110o / -110u	+235

Cowboys Odds
Spread	Total	Moneyline
-6 -115	47 -110o / -110u	-290

Odds via bet365. Get up-to-the-minute NFL odds here.

Saints vs. Cowboys Spread: Cowboys -6
Saints vs. Cowboys Over/Under: 47 points
Saints vs. Cowboys Moneyline: Cowboys -290, Saints +235
Saints vs. Cowboys Pick, Prediction: Cowboys -19.5 alt spread

Las Vegas Raiders at Baltimore Ravens

Sunday, Sep 15

1 p.m. ET

CBS

Raiders Odds
Spread	Total	Moneyline
+8.5 -110	41 -110o / -110u	+325

Ravens Odds
Spread	Total	Moneyline
-8.5 -110	41 -110o / -110u	-425

Odds via bet365. Get up-to-the-minute NFL odds here.

Raiders vs. Ravens Spread: Ravens -8.5
Raiders vs. Ravens Over/Under: 41 points
Raiders vs. Ravens Moneyline: Ravens -425, Raiders +325
Raiders vs. Ravens Pick, Prediction: Ravens to cover the spread

Tampa Bay Buccaneers at Detroit Lions

Sunday, Sep 15

1 p.m. ET

FOX

Buccaneers Odds
Spread	Total	Moneyline
+7.5 -110	51 -110o / -110u	+300

Lions Odds
Spread	Total	Moneyline
-7.5 -110	51 -110o / -110u	-380

Odds via bet365. Get up-to-the-minute NFL odds here.

Bucs vs. Lions Spread: Lions -7.5
Bucs vs. Lions Over/Under: 51 points
Bucs vs. Lions Moneyline: Lions -380, Bucs +300
Bucs vs. Lions Pick, Prediction: Under

New York Jets at Tennessee Titans

Sunday, Sep 15

1 p.m. ET

CBS

Jets Odds
Spread	Total	Moneyline
-4 -110	41 -110o / -110u	-200

Titans Odds
Spread	Total	Moneyline
+4 -110	41 -110o / -110u	+165

Odds via bet365. Get up-to-the-minute NFL odds here.

Jets vs. Titans Spread: Jets -4
Jets vs. Titans Over/Under: 41 points
Jets vs. Titans Moneyline: Jets -200, Titans +165
Jets vs. Titans Pick, Prediction: Titans to cover the spread

Seattle Seahawks at New England Patriots

Sunday, Sep 15

1 p.m. ET

FOX

Seahawks Odds
Spread	Total	Moneyline
-3 -110	38.5 -110o / -110u	-165

Patriots Odds
Spread	Total	Moneyline
+3 -110	38.5 -110o / -110u	+140

Odds via bet365. Get up-to-the-minute NFL odds here.

Seahawks vs. Patriots Spread: Seahawks -3
Seahawks vs. Patriots Over/Under: 38.5 points
Seahawks vs. Patriots Moneyline: Seahawks -165, Patriots +140
Seahawks vs. Patriots Pick, Prediction: Under

Cleveland Browns at Jacksonville Jaguars

Sunday, Sep 15

1 p.m. ET

CBS

Browns Odds
Spread	Total	Moneyline
+3 -105	41.5 -110o / -110u	+140

Jaguars Odds
Spread	Total	Moneyline
-3 -115	41.5 -110o / -110u	-165

Odds via bet365. Get up-to-the-minute NFL odds here.

Browns vs. Jaguars Spread: Jaguars -3
Browns vs. Jaguars Over/Under: 41.5 points
Browns vs. Jaguars Moneyline: Jaguars -165, Browns +140
Browns vs. Jaguars Pick, Prediction: Browns to cover the spread

San Francisco 49ers at Minnesota Vikings

Sunday, Sep 15

1 p.m. ET

CBS

49ers Odds
Spread	Total	Moneyline
-4.5 -110	46.5 -110o / -110u	-240

Vikings Odds
Spread	Total	Moneyline
+4.5 -110	46.5 -110o / -110u	+195

Odds via bet365. Get up-to-the-minute NFL odds here.

49ers vs. Vikings Spread: 49ers -4.5
49ers vs. Vikings Over/Under: 46.5 points
49ers vs. Vikings Moneyline: 49ers -240, Vikings +195
49ers vs. Vikings Pick, Prediction: 49ers to cover the spread

Indianapolis Colts at Green Bay Packers

Sunday, Sep 15

1 p.m. ET

FOX

Colts Odds
Spread	Total	Moneyline
-2.5 -105	41 -110o / -110u	-135

Packers Odds
Spread	Total	Moneyline
+2.5 -115	41 -110o / -110u	+115

Odds via bet365. Get up-to-the-minute NFL odds here.

Colts vs. Packers Spread: Colts -2.5
Colts vs. Packers Over/Under: 41 points
Colts vs. Packers Moneyline: Colts -135, Packers +115
Colts vs. Packers Pick, Prediction: Packers to cover the spread

New York Giants at Washington Commanders

Sunday, Sep 15

1 p.m. ET

FOX

Giants Odds
Spread	Total	Moneyline
+1.5 -110	43.5 -110o / -110u	+105

Commanders Odds
Spread	Total	Moneyline
-1.5 -110	43.5 -110o / -110u	-125

Odds via bet365. Get up-to-the-minute NFL odds here.

Giants vs. Commanders Spread: Commanders -1.5
Giants vs. Commanders Over/Under: 43.5 points
Giants vs. Commanders Moneyline: Commanders -125, Giants +105
Giants vs. Commanders Pick, Prediction: Giants moneyline

Los Angeles Rams at Arizona Cardinals

Sunday, Sep 15

4:05 p.m. ET

FOX

Rams Odds
Spread	Total	Moneyline
+1 -115	48 -110o / -110u	-110

Cardinals Odds
Spread	Total	Moneyline
-1 -105	48 -110o / -110u	-110

Odds via bet365. Get up-to-the-minute NFL odds here.

Rams vs. Cardinals Spread: Cardinals -1
Rams vs. Cardinals Over/Under: Cardinals -110, Rams -110
Rams vs. Cardinals Moneyline: 48 points
Rams vs. Cardinals Pick, Prediction: Rams to cover the spread

Cincinnati Bengals at Kansas City Chiefs

Sunday, Sep 15

4:25 p.m. ET

CBS

Bengals Odds
Spread	Total	Moneyline
+6.5 -110	48 -110o / -110u	+235

Chiefs Odds
Spread	Total	Moneyline
-6.5 -110	48 -110o / -110u	-290

Odds via bet365. Get up-to-the-minute NFL odds here.

Bengals vs. Chiefs Spread: Chiefs -6.5
Bengals vs. Chiefs Over/Under: 48 points
Bengals vs. Chiefs Moneyline: Chiefs -290, Bengals +235
Bengals vs. Chiefs Pick, Prediction: Bengals to cover the spread

Pittsburgh Steelers at Denver Broncos

Sunday, Sep 15

4:25 p.m. ET

CBS

Steelers Odds
Spread	Total	Moneyline
-2.5 -115	36.5 -110o / -110u	-150

Broncos Odds
Spread	Total	Moneyline
+2.5 -105	36.5 -110o / -110u	+125

Odds via bet365. Get up-to-the-minute NFL odds here.

Steelers vs. Broncos Spread: Steelers -2.5
Steelers vs. Broncos Over/Under: 36.5 points
Steelers vs. Broncos Moneyline: STeelers -150, Broncos +125
Steelers vs. Broncos Pick, Prediction: Broncos to cover the spread

Sunday Night Football: Chicago Bears at Houston Texans

Sunday, Sep 15

8:20 p.m. ET

NBC

Bears Odds
Spread	Total	Moneyline
+6 -110	45.5 -110o / -110u	+210

Texans Odds
Spread	Total	Moneyline
-6 -110	45.5 -110o / -110u	-260

Odds via bet365. Get up-to-the-minute NFL odds here.

Bears vs. Texans Spread: Texans -6
Bears vs. Texans Over/Under: 45.5 points
Bears vs. Texans Moneyline: Texans -260, Bears +210
Bears vs. Texans Pick, Prediction: Under

Monday Night Football: Atlanta Falcons at Philadelphia Eagles

Monday, Sep 16

8:15 p.m. ET

ESPN

Falcons Odds
Spread	Total	Moneyline
+6 -110	46.5 -110o / -110u	+210

Eagles Odds
Spread	Total	Moneyline
-6 -110	46.5 -110o / -110u	-260

Odds via bet365. Get up-to-the-minute NFL odds here.

Falcons vs. Eagles Spread: Eagles -6
Falcons vs. Eagles Over/Under: 46.5 points
Falcons vs. Eagles Moneyline: Eagles -260, Falcons +210
Falcons vs. Eagles Pick, Prediction: Under

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