It's the Superclasico of the Americas as Argentina, the defending World Cup champions, take on Brazil, five-time winners, in the biggest game in South American international football.
Here is my Argentina vs. Brazil pick and odds for the World Cup Qualifiers.
Argentina vs. Brazil Pick, Prediction, Odds
Argentina Odds | ||
---|---|---|
Asian Spread | Total | Moneyline |
0.0, -0.5 1.925 | 2.5 +150/-200 | +120 |
Brazil Odds | ||
---|---|---|
Asian Spread | Total | Moneyline |
0.0, -0.5 1.925 | 2.5 +150/-200 | +250 |
- Argentina vs. Brazil moneyline odds: Argentina +120, Draw +220, Brazil +250
- Argentina vs. Brazil over/under: 2.5 Goals (+150/-200)
- Argentina vs. Brazil pick: Under 2.5 Goals, Argentina to Win
I am backing Under 2.5 Goals and Argentina to Win in the Argentina vs. Brazil match.

Argentina Prediction
Argentina enters its second match in a South American Qualifiers double-header with its ticket to the 2026 World Cup almost sealed. A narrow, hard-fought 1-0 win over Uruguay last Friday means they can no longer drop below seventh place in the table, which grants nations a place in an inter-confederation playoff berth, the last chance for a final spot in the World Cup.
The defending World Cup winners are on a roll. Top of the Conmebol qualifiers with 28 points after 13 games, head coach Lionel Scaloni has overseen seven wins across their previous eight World Cup qualifying games at home, and an incredible 11 clean sheets in their past 12 home-played qualifiers.
Still, there are some doubts about how much longer they can keep it going. The win against Uruguay left Argentina on the cusp of another World Cup appearance, but it also left an image of a team that struggled to break down a weaker opponent.
Captain and leader Lionel Messi, set to turn 38 in June, announced he'd miss the double-header, but there hasn't been much talk about how the team will adjust to his slowing pace and ever-decreasing availability.
Forwards Lautaro Martinez (Inter Milan) and Paulo Dybala (Roma), two key men in Scaloni's tenure, are also out. At the same time, midfielder Rodrigo De Paul had to be rested against Uruguay, prioritizing an appearance against Brazil.