Bayer Leverkusen and Bayern Munich face off this Tuesday, March 11, in the second leg of the UEFA Champions League Round of 16. The match kicks off at 4 p.m. (ET) and can be watched on Paramount+.
Bayern Munich secured a convincing 3-0 victory in the first leg, so Leverkusen will try to turn the tie around at home.
Here is my Bayer Leverkusen vs. Bayern Munich prediction and Champions League odds for today's match.
Bayer Leverkusen vs. Bayern Munich Prediction, Pick, Champions League Odds
Bayer Leverkusen Odds | ||
---|---|---|
Spread | Total | Moneyline |
+0.5 -200 | 2.5 -138o /+110u | +172 |
Bayern Munich Odds | ||
---|---|---|
Spread | Total | Moneyline |
-0.5 +138 | 2.5 -138o /+110u | +150 |
- Bayer Leverkusen vs. Bayern Munich moneyline odds: Leverkusen +172, Draw +255, Munich +150
- Bayer Leverkusen vs. Bayern Munich over/under: 2.5 Goals (Over -138, Under +110)
- Bayer Leverkusen vs. Bayern Munich pick: Bayern Munich ML and Both Teams to Score (+320 on DraftKings).
I am backing Bayern Munich ML and Both Teams to Score in the Bayer Leverkusen vs. Bayern Munich match.

Bayer Leverkusen Prediction
Bayer Leverkusen faces a crucial test in their return leg against Bayern Munich in the UEFA Champions League round of 16, following a tough 3-0 defeat in the first leg.
The team, led by Xabi Alonso, is going through a tough moment, with a recent 2-0 loss to Werder Bremen and concerns over the injury to their star player Florian Wirtz, who was forced to leave the field.
With only a 4% chance of overturning the tie, according to Opta, Leverkusen not only needs an epic win but also to overcome a negative streak that could see them lose three consecutive matches, something that hasn't happened since Alonso's arrival at the club in October 2022.
However, the difficulties don't end there for Leverkusen. Although elimination at this stage would mean their only remaining competition would be the DFB-Pokal, all hope is not lost in the Bundesliga.
Bayern Munich leads the league with 61 points, while Leverkusen is in second place with 53 points. While the gap is significant, there is still a long way to go, and although it is difficult, it is not impossible for Alonso's team to fight for the national title.
The players, though with little hope, will try to give everything they have at home, where they avoided defeat in their last three meetings with Bayern (two wins and a draw).
With Wirtz almost certainly sidelined, the key player could be Alejandro Grimaldo, who has proven crucial in past encounters against Bayern, contributing to three goals in the last six games.
Meanwhile, Bayern, who have not had an outstanding away performance in the Champions League, could face a tense night if Leverkusen manages to get a positive result.
The clash at the BayArena promises to be one of those historic matches, and although the odds are against them, Bayer Leverkusen will continue to fight for what remains of the season.

Bayern Munich Prediction
Despite a recent 3-2 defeat to Bochum in the Bundesliga, a team from the bottom of the table, Bayern Munich remains the leader of the Bundesliga and maintains control of the Champions League tie.
Although the loss to Bochum raised some doubts, especially since Bayern played more than half of the match with ten players, Vincent Kompany's team is still one of the favorites to reach the Champions League quarterfinals.
Bayern has had no problems at home during the knockout stages, but their away form has been inconsistent this season, with two losses by large margins.
Key players for Bayern will be Harry Kane, who already scored a brace in the first leg and is one goal away from reaching ten goals in the Champions League this season, and Joshua Kimmich, who will need to lead the midfield and control the game.
With the advantage from the first leg and strength in the Bundesliga, Bayern remains the heavy favorite to advance, but poor away performance could open the door to a surprise.

Bayer Leverkusen vs. Bayern Munich Pick
Bayern Munich remains the clear favorite to win this match. Despite the defeat against Bochum, their individual quality and the advantage in the tie make their victory highly likely.
Leverkusen will be playing at home, and although they are not in their best form, they have the ability to score, especially with players like Grimaldo, who has been key in previous matches against Bayern.
Given the situation in the tie, it is likely that both teams will score at least one goal in this match, making the combination of Bayern's victory and both teams to score a solid option.
Bayer Leverkusen vs. Bayern Munich Pick: Bayern Munich ML and Both Teams to Score (+320 on DraftKings)*
*Market settled based on the result at the end of regular time (including injury time/stoppage time). Extra time and penalty shoot-outs are not included.