Tottenham vs Manchester City Prediction, Pick, EPL Odds

Tottenham vs Manchester City Prediction, Pick, EPL Odds article feature image
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Pictured: Kevin De Bruyne. (Photo by Michael Regan/Getty Images)

Every matchup between the Premier League’s Big Six always draws attention. However, the clash between Tottenham and Manchester City comes with an extra layer of intrigue: one team is experiencing its best form of the season, while the other is going through its worst.

Can Ange Postecoglou’s side make it four league wins in a row? Can Pep Guardiola’s squad recover after their Champions League elimination and loss to Liverpool? We’ll find out after kickoff.

Here is my Tottenham vs. Manchester City prediction and EPL odds for Sunday's match.

Tottenham vs. Manchester City Prediction, Pick, EPL Odds

Man City Logo
Wednesday, Feb 26
2:30 p.m. ET
Tottenham Logo
Man City Odds
SpreadTotalMoneyline
-0.5
-105
3.5
-125o / 100u
+100
Tottenham Odds
SpreadTotalMoneyline
+0.5
-130
3.5
-125o / 100u
+220
Odds via DraftKings. Get up-to-the-minute EPL odds here.
DraftKings Logo
  • Tottenham vs. Manchester City moneyline odds: Tottenham +270, Draw +310, Manchester City +100
  • Tottenham vs. Manchester City over/under: 3.5 (Over -125, Under +100)
  • Tottenham vs. Manchester City pick: Manchester City moneyline and both teams to score

I am backing Manchester City to win and both teams to score in the Tottenham vs. Manchester City match.

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Tottenham Prediction

After a home defeat to a nearly relegated Leicester at the end of January, it seemed Postecoglou’s time was running out. Elimination from the FA Cup and EFL Cup in the span of four days only made things worse for a club desperately chasing silverware.

But the criticism has eased slightly following three consecutive Premier League wins, including a 1-0 victory over Manchester United. Currently sitting in 12th place, their situation is far from ideal, but a win against City could provide a much-needed confidence boost ahead of the last competition they can win: the Europa League.

The Spurs will face AZ Alkmaar in the Round of 16 on March 6 in the Netherlands, with the second leg taking place the following week in London. Against City, they will rely on James Maddison, who has been in great form since returning from injury, along with key attacking players Son Heung-min, Brennan Johnson, and Dejan Kulusevski.

However, Tottenham is dealing with key absences. Defenders Cristian Romero, Micky van de Ven, Radu Dragusin, and forwards Dominic Solanke and Richarlison remain sidelined. On the bright side, Timo Werner has returned to training and could get some minutes.

Header First Logo

Manchester City Prediction

Guardiola is experiencing his toughest spell in nearly nine years at Manchester City, and rebuilding this team could be one of the biggest challenges of his career. The early Champions League elimination against Real Madrid was a massive blow, and the team has yet to show any real signs of recovery.

City sits fifth in the Premier League, with Champions League qualification for next season as their primary goal. With just a five-point gap over 10th-placed Fulham, every match is crucial.

To make matters worse, Erling Haaland has missed the last few games due to injury. The Norwegian striker, who has already scored 19 Premier League goals this season, remains doubtful for this match. If he’s unavailable, Omar Marmoush will likely lead the attack.

City will also be without John Stones and Manuel Akanji, while Rodri’s long absence further weakens their midfield. Missing the Ballon d’Or winner has been one of the biggest factors behind their struggles, and at this point, their priority is to regain confidence and salvage the season.


Header First Logo

Tottenham vs. Manchester City Pick

Tottenham has already defeated Manchester City twice this season: a 2-1 win in the EFL Cup in October 2024 and a stunning 4-0 victory at the Etihad Stadium in the Premier League the following month.

Spurs enter this match in better form, yet the odds still have them as underdogs. That’s because, despite their struggles, City remains higher in the standings and boasts a stronger squad. The crisis has to end at some point, and the giant will rise sooner or later.

Both teams have defensive vulnerabilities, whether due to injuries or poor form. This significantly raises the chances of both teams scoring, making for an exciting and thrilling match.

Tottenham vs. Manchester City Pick: Manchester City to win and both teams to score (+175, DraftKings)

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