Sinner vs Medvedev Odds
| Sinner Odds | -275 |
| Medvedev Odds | +215 |
| Over/Under | 39.5 (-105 / -125) |
| Time | How to Watch | Wednesday, 9 p.m. ET | ESPN |
| Odds via DraftKings. For tips on how to watch US Open tennis, click here. | |
Our second US Open quarterfinal of the day on Wednesday will be a much-anticipated rematch between the two current favorites to win the US Open, Jannik Sinner and Daniil Medvedev.
The World No. 1 will be looking for sustained dominance in the head-to-head over Medvedev and to move on step closer to his first US Open title, while Medvedev eyes the opportunity to capture that trophy for a second time with more good play in New York.
Let's get into the best way to bet on Sinner vs Medvedev on Wednesday at the US Open.
Jannik Sinner
With a 54-5 record this season, it's hard to call Jannik Sinner anything other than dominant. He's only captured one of this season's Grand Slams, which came eight months ago at the Australian Open, but he's already won a career-high five tournaments and has lost just twice since bowing out of the French Open in the semifinals against Carlos Alcaraz.
That's not to say it's all been neat-and-tidy for the Italian. There's the off-court stuff, sure, with news of a positive doping test coming out just before the US Open. There's been a lot of on-court drama, too, as Sinner's battled a hip injury he picked up back in May which forced him to miss almost a month and was reportedly quite serious.
In the months since, Sinner has done well to shrug off the injury concerns, but they returned just a few weeks ago in Cincinnati where he was walking with a noticeable limp. He's come through his draw here without any cause for concern, however, other than a painful-looking slide in the final set of his fourth-round win over Tommy Paul.
Sinner matched an incredibly high level from Paul to win in straight sets on Monday and has now only dropped one set — which happened to be the first he played here this week. He's looked hard to beat — like the World No. 1 should.
Daniil Medvedev
There weren't too many people saying Medvedev would be one of the final four players remaining in this draw after a dreadful summer on the hard courts, but it seems those losses have actually done him a lot of good.
With early exits in Montreal and Cincinnati, as well as a stay at the Paris Olympics which lasted just three matches, Medvedev appears refreshed and as crisp as ever this week in Queens. It's not a surprise that he's instantly found his form again on these courts, considering he's always found his best level at this tournament.
Medvedev, who has reached at least the semis here in four of the last five years, has dissected every one of his opponents over the first week of play with just one lost set in four matches. He may not have had the toughest draw on paper, but in dropping just four games against Nuno Borges — a player who had taken him four sets in Australia earlier this year and played him close in Halle — he proved a lot about where his game's at.
The task at hand here will be a tall one, considering Sinner has gotten the best of him in five of their last six meetings. The good news is that Medvedev won their most recent encounter, which was just a couple of months ago at Wimbledon.
Sinner vs Medvedev Pick
Though Sinner has controlled most of the recent head-to-head after dropping his first six matches against Medvedev, the expert strategist has experimented with some fruitful tactics in each of their three encounters this year. In going for more aggressive shots — something that was born out of necessity in the Australian Open final after four marathon matches — Medvedev was able to win points quickly and take it to Sinner before his tank ran empty. We saw some of that at Wimbledon, too, with the faster courts aiding Medvedev in that quest, and now it's fair to say he's got several ways he can approach this match.
We haven't seen a damning matchup stop Medvedev on these courts before, considering he took out Novak Djokovic in the final here three years ago and got past Carlos Alcaraz at last year's US Open as a big underdog. He has always played his best here, and I think that should leave Sinner in a slightly uncomfortable situation.
There's no question the Italian is striking the ball better than anyone left in the draw, but I question what will happen when he plays the toughest backboard in the world and is forced to play a large collection of long rallies and run all around the court. There's a good chance that hip — which he was really feeling after a grueling run in Cincinnati just a few weeks ago — begins to bother him again with all the punches he takes, and that should let Medvedev into the match.
It's a hard call as to how exactly to back Medvedev, but I see the game spread as an attainable cover even in a four-set defeat.
