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After the conclusion of the first round on Tuesday, the US Open will roll out its second round matches straight away on Wednesday.
Our team of experts has evaluated a number of matches that we believe have betting value.
Read on to see which spots we're targeting on a loaded day of tennis.
Matches are listed in chronological order. Match times are subject to change and many will be played after the projected start time. Read here for advice on watching the US Open.
Pablo Carreno Busta vs. Alexander Bublik
11 a.m. ET
Pablo Carreno Busta is a heavy favorite against Alexander Bublik, but these two have played some thrillers in the past.
Kenny Ducey explains why you can use that knowledge to your advantage.
Shelby Rogers vs. Viktoria Kuzmova
11 a.m. ET
American Shelby Rogers secured a comeback victory to get her US Open underway, but David Gertler believes she could be tested again.
Read on to see why the underdog has more value in this contest.
Alex de Minaur vs. Cristian Garin
11 a.m. ET
Rounding out the earliest slate of matches is this Wimbledon rematch.
We could be in store for another good match, says Ducey, who is looking to target the spread.
Andy Murray vs. Emilio Nava
12 p.m. ET
Former US Open champion Andy Murray earned a nice first round win against Francisco Cerundolo, and he now has American Emilio Nava in his way.
Carmine Carcieri breaks down the battle of youth versus experience.
Shuai Zhang vs. Anna Karolina Schmiedlova
1 p.m. ET
One player that absolutely loves these New York courts is Shuai Zhang, and she's a big favorite to advance on Wednesday.
Jonathan Reid looks at the match she has versus Anna Karolina Schmiedlova.
Nick Kyrgios vs. Benjamin Bonzi
1:30 p.m. ET
Benjamin Bonzi won't be an easy out for the ever-talented Nick Kyrgios, says Luke Holmberg.
See why he's looking for a spread play against Kyrgios in the afternoon.
Felix Auger-Aliassime vs. Jack Draper
1:30 p.m. ET
While Kyrgios takes on Bonzi, Felix Auger-Aliassime will be duking it out with Jack Draper.
Holmberg has you covered with another blockbuster match preview.
Sebastian Korda vs. Tommy Paul
2:30 p.m. ET
An All-American battle that features some of the top men that the United States has to offer headlines the middle of the day.
See why Carcieri has faith in the elder American to get the job done.
Liudmilla Samsonova vs. Leylah Fernandez
5 p.m. ET
Two long-shot candidates to make a run at the title will square off in the late-afternoon.
Gertler previews a big-hitting battle between Liudmilla Samsonova and Leylah Fernandez.
Serena Williams vs. Anett Kontaveit
7 p.m. ET
Serena Williams gets another primetime Ashe slot for a match that could be her last.
Her opponent will be Anett Kontaveit, and Gertler is wary of taking action on the underdog.
Beatriz Haddad Maia vs. Bianca Andreescu
9 p.m. ET
It's a straight pick 'em to close off the action, as Beatriz Haddad Maia takes on former champion Bianca Andreescu.
Reid highlights which of the sides he believes will move on to a Friday spot.
