The Detroit Tigers host the Baltimore Orioles on April 25, 2025. First pitch from Comerica Park is scheduled for 6:40 p.m. EDT; the game will be broadcast on MLB Network.
Find my Orioles vs Tigers prediction and same-game parlay picks below.
My Orioles vs Tigers Prediction
- Orioles +1.5
- Ryan O'Hearn Over 1.5 Total Bases
- Gunnar Henderson Over 0.5 RBIs
Parlay Odds: +660 (Fanatics)
Orioles vs Tigers Odds
| Orioles Odds | ||
|---|---|---|
| Moneyline | Total | Run Line |
+110 | 8.5 -112 / -108 | +1.5 -185 |
| Tigers Odds | ||
|---|---|---|
| Moneyline | Total | Run Line |
-130 | 8.5 -112 / -108 | -1.5 +154 |
Orioles vs Tigers Preview, Parlay Picks
Leg 1: Orioles +1.5
The Orioles are much better than their early-season record indicates.
The O's won a much-needed game on Thursday over the Washington Nationals to avoid a sweep.
Brandon Young was solid in his first start of the season last week against the Cincinnati Reds.
Young will be good enough on Friday to keep the O's close and let the offense carry the weight.
Leg 2: Ryan O'Hearn Over 1.5 Total Bases
The veteran has crushed right-handed pitching throughout his career.
Ryan O’Hearn hit .264 with 15 home runs against righties last season and has a .294 average this season.
The 31-year-old is 3-8 (.375) in his career against Casey Mize.
Gunnar Henderson Over 0.5 RBIs
One reason for Baltimore's early-season struggles is Gunnar Henderson's struggles.
Henderson is batting .213 with just three runs batted in.
But Henderson is too talented not to snap out of his drought and has excellent value to knock in a run at plus money tonight.
Orioles vs Tigers Parlay
- Orioles +1.5
- Ryan O'Hearn Over 1.5 Total Bases
- Gunnar Henderson Over 0.5 RBIs
Parlay odds: +660 (Fanatics)
