Cubs vs Phillies Prediction, Pick, Odds for Monday, September 23

Cubs vs Phillies Prediction, Pick, Odds for Monday, September 23 article feature image
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Photo by John Fisher/Getty Images. Pictured: Aaron Nola (Phillies)

The Philadelphia Phillies (92-64) host the Chicago Cubs (80-76) on Monday afternoon at Citizens Bank Park.

First pitch for this NL series opener is scheduled for 6:40 p.m. ET on MLB.TV.

Find my Cubs vs Phillies prediction and pick on the run line for Monday, plus the latest MLB odds for September 23, below.


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Cubs-Phillies Prediction

  • Cubs-Phillies picks: Phillies -1.5

My Cubs vs Phillies best bet is on Philadelphia's run line, where I see value at +120. The best line is available at DraftKings, as well as other sportsbooks — make sure to find the best odds by checking our live MLB odds page.


Cubs vs Phillies Odds

Cubs Logo
Monday, Sept. 23
6:40 p.m. ET
MLB.TV
Phillies Logo
Cubs Odds
MoneylineTotalRun Line
+150
8
-110 / -110
+1.5
-142
Phillies Odds
MoneylineTotalRun Line
-180
8
-110 / -110
-1.5
+120
Odds via DraftKings . Get up-to-the-minute MLB odds here.
DraftKings  Logo

Cubs vs Phillies Projected Starting Pitchers

RHP Nate Pearson (CHC)StatRHP Aaron Nola (PHI)
2-2W-L12-8
0fWAR (FanGraphs)2.8
4.71 / 4.47ERA /xERA3.54 / 3.76
4.48 / 3.77FIP / xFIP4.04 / 3.53
1.33WHIP1.17
18.8%K-BB%17.5%
34.8%GB%43.8%
128Stuff+104
99Location+105

Check out our MLB Betting Hub for more previews from today's slate.

Tony Sartori's Cubs vs Phillies Preview

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Chicago Cubs Betting Preview: Fade This Pitching Staff

Nate Pearson is expected to work the first inning or two as an opener while Hayden Wesneski is expected to lead the bulk of the relief in a scheduled bullpen day.

With that said, you should look to fade this pitching staff on Monday evening.

Pearson possesses a 4.71 ERA and 1.33 WHIP through 57 appearances on the mound this season. His underlying metrics are equally poor, as the right-hander ranks in the bottom-third of the league in xERA, average exit velocity, barrel rate and hard-hit rate.

Meanwhile, Wesneski also ranks in the bottom half of the league in both xERA and barrel rate.

We also don't know how much burn either guy is going to get, but we do know that this Chicago bullpen ranks in the bottom half of the league in xFIP.

That just leaves the hitting, which is another disadvantage for the Cubs in this game. They trail Philadelphia in runs scored per game, hits per game, BA, OBP, SLG, OPS, home runs and stolen bases.

Furthermore, this current Cubs lineup possesses a fade-worthy .178 BA, .287 SLG and .226 wOBA through 137 combined career plate appearances against Aaron Nola.


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Philadelphia Phillies Betting Preview: Nola Looking Great

Nola has put together another strong season. He's 12-8 through 31 starts with a 3.54 ERA and 1.17 WHIP.

His analytics are equally strong, as the right-hander ranks in the top half of the league in xERA, average exit velocity, strikeout rate, walk rate, barrel rate and hard-hit rate.

Following Nola is a bullpen that ranks in the top 10 in both FIP and xFIP.

This pitching staff should also receive plenty of run support, considering that Philadelphia ranks in the top 10 in runs scored per game, hits per game, BA, OBP, SLG, OPS, home runs and stolen bases.


Cubs vs Phillies Prediction, Betting Analysis

There's not a single advantage that Chicago possesses in this matchup.

Nola outranks both Pearson and Wesneski in ERA, xERA, walk rate and barrel rate.

Philadelphia's bullpen also outranks the Cubs' in both FIP and xFIP.

And, as mentioned above, the clear lineup advantage also goes to the Phillies.

Finally, Philadelphia is playing on its home diamond, a venue where it's winning at a 67% clip this season.

On the other hand, Chicago has lost 51% of its road games.

Pick: Phillies -1.5 (+120 | Play to +115)

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Moneyline

I'm going to pass on the moneyline. While I like Philadelphia to win this game, I would rather take a chance on its run line rather than lay the 78 cents on its moneyline.


Run Line (Spread)

I'm betting the Phillies -1.5 in this game.


Over/Under

I'm also going to pass on the over/under. There are too many contradicting variables for my liking in this market, such as Philadelphia's explosive lineup and Nola's excellent pitching.


Cubs vs Phillies Betting Trends

  • 88% of the bets and 97% of the money is on the Phillies to win on the moneyline against the Cubs.
  • 89% of the bets and 96% of the money is on the Phillies to cover the spread against the Cubs.

Cubs Betting Trends

Phillies Betting Trends


Cubs vs Phillies Weather

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About the Author
Tony Sartori is a writer for The Action Network. He has published over 1,000 sports betting articles for various media outlets since graduating from college in 2022.

Follow Tony Sartori @tony_sartori on Twitter/X.

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