The Minnesota Twins host the Chicago White Sox on April 24, 2025. First pitch from Target Field is scheduled for 1:10 p.m. EDT; the game will be broadcast on CHSN.
The Minnesota Twins are eyeing a sweep against the White Sox, who have just five wins — the lowest mark in baseball. The Twins enter as a heavy -225 favorite with -105 odds on the -1.5 run line.
Find my White Sox vs Twins predictions below, as well as probable pitchers, betting trends, and more.
My White Sox vs Twins Prediction
- White Sox vs Twins picks:Twins -1.5 (-110 | Play to -140)
My White Sox vs Twins best bet is on the Twins run line. Make sure to find the best odds by checking our live MLB odds page.
White Sox vs Twins Odds
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -110 | 8 -110o / -110u | +190 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -110 | 8 -110o / -110u | -235 |
White Sox vs Twins Projected Starting Pitchers
| Shane Smith (CHW) | Stat | Chris Paddack (MIN) |
|---|---|---|
| 0-1 | W-L | 0-2 |
| 0.4 | fWAR (FanGraphs) | -0.1 |
| 2.82/4.40 | ERA /xERA | 7.27/4.67 |
| 3.88/4.96 | FIP / xFIP | 5.85/4.75 |
| 0.94 | WHIP | 1.56 |
| 7.8% | K-BB% | 7.5% |
| 42.9% | GB% | 40.7% |
| 94 | Stuff+ | 98 |
| 98 | Location+ | 116 |
Sean Paul’s White Sox vs Twins Preview
Chicago White Sox Betting Preview: Offense Still Stuck in the Mud
Shane Smith's last start was a real “prove it” spot.
He walked into historic Fenway Park with rowdy fans on a weekend day and delivered a solid outing, but nothing jaw-dropping, allowing three runs across 4 2/3 innings. The rookie righty now boasts a 2.82 ERA with a 3.88 FIP and a 4.40 xERA.
A lot of pitching success can be attributed to BABIP luck. Smith is the beneficiary of BABIP luck, as opposing batters have a .194 average when putting balls in play.
The White Sox offense is brutal. That's the only word that fairly describes just how bad the bats are.
Since April 1st, the White Sox have posted a 61 wRC+, ranking 29th out of 30 MLB teams. Chicago pairs the second-lowest wRC+ with the second-lowest batting average (.199) and second-lowest isolated power (.087).
For further context on the White Sox's dreadful offensive start, Andrew Benintendi spent a minimum stay on the injured list and still leads the team with four homers. The next closest are Andrew Vaughn (three) and Luis Robert (two). We're looking at the least inspiring offense in baseball.
Even if the White Sox cobble together enough runs for an early lead, their bullpen will probably implode. They led in the sixth inning on Wednesday and still managed to lose by three runs.
The White Sox need some length from Smith after a full-fledged bullpen game yesterday, which featured seven pitchers.
Minnesota Twins Betting Preview: Paddack Redemption at Perfect Time
Chris Paddack started the year in the worst fashion imaginable, allowing nine runs to the White Sox. Then, Paddack coupled his terrible first start with an ugly second start versus the Astros.
Since then? It looks like the old Paddack.
He's back to striking out hitters — after punching out only four in his first two outings, he's responded with 11 strikeouts across his past two games.
I don't foresee Paddack becoming an ace or anything, but can you comfortably back him here? Absolutely.
He has a 7.27 ERA, which is down from 14.27 two starts ago, with expected stats in the mid-fours. Everything suggests that Paddack will turn it around.
I trashed on the White Sox offense plenty, so I have to keep it fair here. The Twins' offense isn't anything special, with a 91 wRC+ that ranks 21st in MLB since April began.
There is room for optimism, though.
It begins with the sudden rise of prospect Luke Keaschall. He's played just four games, but his plate discipline (17% walk rate) and pristine strikeout rate (11%) make him an outstanding top-of-the-order bat. Four other Minnesota hitters boast a wRC+ above 100, including Byron Buxton.
However, one piece is missing. Carlos Correa, the Twins' highest-paid bat, looks long in the tooth. He's hitting .177 with a 58 wRC+ and even worse hard-hit numbers.
White Sox vs Twins Prediction, Betting Analysis
Paddack is due for even more positive regression, and there's no better recipe for a struggling pitcher than facing the White Sox. That'll lead to favorable results from the pitchers most of the time, and Paddack could cruise through six innings.
The Twins are just the better team from top to bottom. I can't see the White Sox covering the run line in the series finale.
Pick: Twins -1.5 (-110 | Play to -140)
