The Seattle Mariners host the Houston Astros on Wednesday, April 9, 2025. First pitch from T-Mobile Park is scheduled for 4:10 p.m. ET; the game will be broadcast on ROOT Sports NW.
Find my Astros vs Mariners prediction below.
My Astros vs Mariners Prediction
- Astros vs Mariners picks: Luis Castillo Under 3.5 Strikeouts
My Astros vs Mariners best bet is for Luis Castillo to record under 3.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Mariners Odds
April 9, 2025
4:10 p.m. EDT
ROOT Sports NW
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -161 | 7.5 -102o / -118u | -132 |
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +135 | 7.5 -102o / -118u | +112 |
Odds via BetMGM. Get up-to-the-minute MLB odds here.
Alex Kolodziej’s Astros vs Mariners Prediction, Betting Analysis
The Seattle Mariners will trot out right-handed pitcher Luis F. Castillo on Wednesday and the best bet for the 4:05 p.m. ET matchup is for Castillo to finish with under 3.5 strikeouts.
