There are 16 games on tap for the Saturday, April 26, baseball slate and our betting experts have come through with four MLB best bets.
Among their MLB picks and predictions for Saturday: a moneyline pick for the first game between the Orioles and Tigers and three strikeout props for Yusei Kikuchi, Hunter Greene and Roki Sasaki.
Find our four MLB best bets for Saturday below; you can also find a parlay of all four picks.
MLB Best Bets, Picks, Props — Saturday 4/26
| Game | Time (ET) | Pick |
|---|---|---|
  | 1:10 p.m. | |
  | 2:10 p.m. | |
  | 3:10 p.m. | |
  | 9:10 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Orioles vs Tigers Best Bet: Mize Rising?
The Orioles–Tigers series opener got rained out on Friday, but I'm still on the same bet.
Tigers right-hander Casey Mize was a top draft pick, but he struggled to put things together at the MLB level for a few years. However, he made some strides in 2024 and has had a fantastic start to 2025.
He has allowed one or fewer runs in three of his four starts, and he will be pitching at home in a pitcher-friendly environment.
I trust Mize more than Orioles rookie Brandon Young on the other side. Detroit's offense also remains an underrated unit.
Pick: Tigers Moneyline (-118)
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Angels vs Twins Prop Pick: Kikuchi Strikeouts
By Will Priester
We are paying some juice here, but I think this is a good line to attack.
If you look at this season's numbers in the RotoGrinders PlateIQ tool, there are strikeouts to be had in this Minnesota lineup.
Asking for one strikeout or more per inning from Yusei Kikuchi doesn't seem like a stretch. He's struck out six in three of his five starts this season.
Pick: Yusei Kikuchi Over 5.5 Strikeouts (-148)
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Reds vs Rockies Plus-Money Strikeout Prop
By Will Priester
I'm trusting Hunter Greene to get it done against this Rockies lineup.
