Pirates vs Dodgers Prediction, Pick, Odds for Friday, April 25

Pirates vs Dodgers Prediction, Pick, Odds for Friday, April 25 article feature image
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Paul Skenes and Yoshinobu Yamamoto (Imagn Images)

The Los Angeles Dodgers host the Pittsburgh Pirates on April 25, 2025. First pitch from Dodger Stadium is scheduled for 10:10 p.m. EDT; the game will be broadcast on SportsNet LA.

Find my MLB betting preview and Pirates vs Dodgers prediction below, as well as probable pitchers, betting trends, injury reports, and more.

Quickslip

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My Pirates vs Dodgers Prediction

  • Pirates vs Dodgers picks: Dodgers -1.5 (+110 | Play to +100)

My Pirates vs Dodgers best bet is on the Dodgers to cover the spread. Make sure to find the best odds by checking our live MLB odds page.


Pirates vs Dodgers Odds

Pirates Logo
Friday, Apr 25
10:10 p.m. ET
SportsNet LA
Dodgers Logo
Pirates Odds
SpreadTotalMoneyline
+1.5
-130
7
-105o / -115u
+170
Dodgers Odds
SpreadTotalMoneyline
-1.5
+110
7
-105o / -115u
-210
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Pirates vs Dodgers Projected Starting Pitchers

RHP Yoshinobu Yamamoto (LAD)StatRHP Paul Skenes (PIT)
3-1W-L2-2
1.0fWAR (FanGraphs)1.2
0.93/2.18ERA /xERA2.87/2.06
2.02/1.81FIP / xFIP2.00/2.59
0.86WHIP0.80
28.7%K-BB%22.0%
63.5%GB%56.6%
97Stuff+108
114Location+110

Doug Ziefel's Pirates vs Dodgers Preview

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Los Angeles Dodgers Betting Preview: Yamamoto Will Trouble the Pirates

This is a marquee pitching matchup, starting with Yoshinobu Yamamoto.

Yamamoto has started 2025 looking like a Cy Young candidate, sporting a 0.93 ERA through five starts.

He's been dominant in all areas, ranking in the 94th percentile among qualified pitchers in strikeout rate and ground ball rate, as well as the 91st percentile in Expected ERA.

That all means that he's been tough to hit, and when Yamamoto has allowed contact, it's been on the ground.

This matchup with Yamamoto is trouble for the Pittsburgh Pirates, who come in sporting the eighth-lowest team batting average and the 10th-worst whiff rate. On top of that, they hold the 12th-highest groundball rate.

With all their tendencies playing into the strengths of Yamamoto, it's hard to predict much positive regression for the Pirates' lineup tonight, even if other metrics show they are due for some.


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Pittsburgh Pirates Betting Preview: Can Skenes Deal With the Dodgers?

There certainly is not much of a gap on the mound as Paul Skenes will face the defending World Series champions tonight.

Like his counterpart, Skenes has been stellar, holding a 2.87 ERA and 0.80 WHIP while producing whiffs and groundballs with the best of them.

However, he's in for his toughest test to date with this Dodgers lineup. Los Angeles ranks second among MLB lineups in Expected wOBACON, despite holding a .231 team batting average. The Dodgers are seeing the ball very well, but they haven't been rewarded for it yet.

While I believe in Skenes' ability to navigate this lineup, it's the arms behind him that could ruin this one for Pittsburgh.

The Pirates' bullpen has been surprisingly solid to start this season, ranking eighth in ERA. However, their collective xFIP of 4.15 tells a much different story, indicating negative regression is on the horizon.

With the Dodgers' bats trending up and the majority of the Pirates' staff due to blow up, Los Angeles should have a good window to break this game open.


Pirates vs Dodgers Prediction, Betting Analysis

This is a must-watch matchup as we have two of the best young arms in baseball set to duel tonight.

It's very possible they could both be excellent, and the Dodgers cover the run line because of the Pirates' impending bullpen woes.

However, don't be surprised to see the Dodgers get Skenes into some trouble, which would only amplify their damage late in this matchup.

Back the Dodgers to cover the run line.

Pick: Dodgers -1.5 (+110 | Play to +100)


Moneyline

The Dodgers' moneyline has less value than the run line.


Run Line (Spread)

I am taking the Dodgers on the run line.


Over/Under

I am avoiding the total.


Pirates vs Dodgers Betting Trends


Pirates vs Dodgers Weather


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About the Author
Doug is a college football, college basketball and MLB contributor at the Action Network. He produces content centered around actionable advice with the goal of helping readers become better bettors. He studied journalism at Rutgers and has previously covered the New York Mets, Indianapolis Colts, and Mid-Atlantic region for Perfect Game.

Follow Doug Ziefel @DougZiefel on Twitter/X.

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