The Cincinnati Reds host the St. Louis Cardinals on April 28, 2025. First pitch from Great American Ball Park is scheduled for 6:40 p.m. ET; the game will be broadcast on MLB Network.
The Reds will host the Cardinals after coming home from a sweep in Colorado. Cincinnati will be looking to build on this momentum and continue its winning ways.
Find my MLB betting preview and Cardinals vs Reds prediction below, as well as probable pitchers, betting trends, injury reports and more.
Cardinals vs Reds Prediction, Parlay Picks
- Elly De La Cruz to Record a Hit
- Reds ML
Parlay Odds: +150 (BetMGM)
Cardinals vs Reds Odds
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +160 | 9 -112o / -108u | +102 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -192 | 9 -112o / -108u | -122 |
Cardinals vs Reds Projected Starting Pitchers
| RHP Andre Pallante (STL) | Stat | RHP Nick Martinez (CIN) |
|---|---|---|
| 2-1 | W-L | 0-3 |
| -0.2 | fWAR (FanGraphs) | 0.3 |
| 4.05/4.69 | ERA /xERA | 5.40/4.42 |
| 5.41/3.76 | FIP / xFIP | 4.29/4.27 |
| 1.28 | WHIP | 1.39 |
| 5.4% | K-BB% | 12.2% |
| 67.4% | GB% | 31.3% |
| 88 | Stuff+ | 94 |
| 106 | Location+ | 110 |
Chilly Bets’s Cardinals vs Reds Preview
Elly De La Cruz to Record a Hit
We're taking Elly De La Cruz to increase his hit streak to 12 on Monday. He’s been seeing the ball well and, across the streak, has also knocked three home runs to get his season total to five.
He should have no problem getting one on Monday, as Palante has struggled to start his season.
Reds ML
We're also taking the Reds to win on Monday. They've won four straight and are back home, while the Cardinals have gone 3-7 over their last 10 games.
Back the team on the upward trajectory and stay away from the one that's inconsistent.
Cardinals vs Reds Parlay
- Elly De La Cruz to Record a Hit
- Reds ML
Parlay odds: +150 (BetMGM)
Cardinals vs Reds Betting Trends
