Clemson vs. McNeese State Odds
| Clemson Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-7.5 -102 | 135.5 -110o / -110u | -360 |
| McNeese State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+7.5 -120 | 135.5 -110o / -110u | -280 |
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The 2025 NCAA Tournament field has been announced and Clemson will take on McNeese State in Round 1 of the Midwest region. Here's everything you need to know about Clemson vs. McNeese State odds, spread and more.
Clemson opened as a 7.5-point favorite over McNeese in the first round of the NCAA Tournament. The total is set at over/under 135.5 points scored by both teams combined.
Clemson vs McNeese State Analysis
Clemson’s reward for its highest seed since 2018 is a very capable McNeese team, led by former LSU coach Will Wade. McNeese has lost just one game since Christmas, absolutely cruising through the Southland Conference.
In the Cowboys’ chances against top competition this season, they’ve put up quite a fight. McNeese lost to Alabama by just eight points in Tuscaloosa and Mississippi State by just three points (on semi-neutral court in Tupelo).
This game should have one of the first round’s lowest totals, thanks to two slowly-paced teams.
If anything, that cracks the door even wider for a McNeese upset win, lowering the sample size of the game and letting a hot shooting night take on an outsized effect.
Last season, when McNeese was roughly the same caliber of team as a 12-seed, the Cowboys lost to a run-and-gun Gonzaga team by 20 plus. The nature of this game with Clemson should play more into the Cowboys’ hands.
–Shane McNichol
For more coverage of the 2025 NCAA Tournament and Selection Sunday, make sure to check out our experts' live reactions to the bracket reveal and the Selection Sunday live show, where you can get their instant analysis on every matchup as well as some early insights to help you make your bets.
