College Basketball Best Bets: 3 Picks, Predictions for Wednesday’s Games

College Basketball Best Bets: 3 Picks, Predictions for Wednesday’s Games article feature image
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Photo by Candice Ward/Getty Images. Pictured: Milos Uzan (Houston)

The Battle 4 Atlantis and Maui Invitational championship game take centerstage today, and there's betting value across the board for college basketball as Feast Week continues.

I'm targeting three specific games, including a late-night battle in Vegas between Notre Dame and Houston.

So, here's college basketball best bets, including three picks and predictions for Wednesday's games on November 27.


College Basketball Best Bets

The team logos in the table below represent each of the matchups that our college basketball betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Lindenwood Lions LogoMissouri Tigers Logo
6:30 p.m.
Davidson Wildcats LogoArizona Wildcats Logo
7:30 p.m.
Notre Dame Fighting Irish LogoHouston Cougars Logo
12:30 a.m.
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NCAAB Odds page, which automatically surfaces the best lines for every game.

Lindenwood vs. Missouri

Lindenwood Lions Logo
Wednesday, Nov. 27
6:30 p.m. ET
ESPN+
Missouri Tigers Logo
Missouri -28.5
FanDuel Logo

As a true Mizzou alum, my natural instinct is to be pessimistic about my Tigers and bet against them at every chance I get.

However, this year’s Tigers squad has shown real ability to crush inferior competition — a departure from Mizzou teams of recent history.

Mizzou has taken a battering ram to lesser opponents in three straight games, winning by an average of 52 points. Lindenwood is one of the 15 worst teams in the country and has neither the offensive firepower nor the defensive fortitude to keep pace.

Mizzou’s guards have discovered their outside shot this season. Caleb Grill has been an inferno off the bench, knocking down over 55% of his 3-ball tries. It’s almost as if he’s offended at the bad competition coming to Columbia by the way he’s been shooting the cover off the ball.

Mizzou’s depth gives it an upper hand, with multiple guys able to hurt the opposition on offense. Dennis Gates has played the third-most bench minutes in the country to date.

Lindenwood defends the 3-point arc like a drunk matador defends a bull – that is, very very poorly. The Lions rank 335th in 3-point attempt rate allowed and 340th in 3-point percentage allowed this season.

That's a bad recipe against a Mizzou team that loves the long ball.

The Tigers also have a massive physicality advantage tonight and should name their number on the offensive glass, as well as the charity stripe.

Lindenwood’s only prayer for competing is shooting variance.

Lions, Tigers and blowouts, oh my! Mizzou crushes in-state “rival” in CoMo tonight.

Pick: Missouri -28.5 (Play to -30)


Davidson vs. Arizona

Davidson Wildcats Logo
Wednesday, Nov. 27
7:30 p.m. ET
ESPN2
Arizona Wildcats Logo
Davidson +16
Caesars Sportsbook Logo

The Battle 4 Atlantis undercard features Davidson and Arizona, the only first round matchup between two non-power teams (excluding Gonzaga, because it’s Gonzaga).

It’s also the biggest spread, with the Zona Cats favored heavily over the Dave Cats.

Arizona has a propensity to blow out inferior competition under Tommy Lloyd — see a 58-point win against Old Dominion and a 29-point win against Canisius — but there’s reason to believe the lesser Wildcats can hang around.

Davidson is off to its best start of the Matt McKillop era, and though it hasn’t played a top-tier schedule, the early returns are strong.

Strong rim deterrence has been a key to Davidson’s success. The Wildcats rank fifth nationally in field goal attempt rate allowed at the rim, thanks in no small part to shot-blocking extraordinaire Sean Logan.

With Logan and fellow 6-foot-10 starter Reed Bailey up front, the Wildcats have the interior fortitude to stand up to Arizona on the glass and protect the paint.

Arizona is off to a rockier start mainly due to the play of Caleb Love, who has gone from an All-American to the third option overnight. He’s shooting just 21% from 3 and sub-50% from 2 and generally looks like a different player.

Perhaps he finds his rhythm against a Davidson perimeter that won’t be nearly as tough as Duke or Wisconsin, but it’s a concerning trend going against an experienced team like Davidson.

Davidson should take advantage of Arizona’s early foul foibles, as one of its key avenues for scoring has been the charity stripe. Arizona ranks just 297th in free throw attempt rate allowed, with several players picking up foul trouble consistently.

Expect feisty Davidson to hang around and pester this superior Arizona squad all night long.

Pick: Davidson +16 (Play to +15)


Notre Dame vs. Houston

Notre Dame Fighting Irish Logo
Wednesday, Nov. 27
12:30 a.m. ET
TBS
Houston Cougars Logo
Houston -16.5
FanDuel Logo

For the night owls out there, Notre Dame and Houston clash in Vegas in the Players Era Tournament, a tournament that pays money to the winning team — NIL baby!

Houston has two losses in November for the first time since 2020, though those losses have come to two of the best programs in the country in Auburn and Alabama — and the Cougars had strong chances to win both.

Notre Dame comes in limping — both literally and figuratively — after an OT loss to Rutgers. In that contest, the Irish lost star guard Markus Burton to an injury for the foreseeable future.

Though the market has adjusted for the Burton loss (line is five points above KenPom), it hasn’t gone far enough. There is no margin for error when facing Houston, a team that physically overwhelms its opposition in every facet of the game.

Burton has had a massive impact on Notre Dame this season, per CBB Analytics' on/off stats. He runs the point, is the primary scoring option and is the primary creator.

Houston’s long, tenacious perimeter will be a problem for the Burton-less Irish. Scoring will be near-impossible as the Irish look to crack the vaunted Houston interior.

Notre Dame has two hopes: slow this game to sub-60 possessions and hope to be hot from 3. Both hopes could happen, and Micah Shrewsberry is one of the best coaches in college basketball, but if Notre Dame is even a little off with its perimeter shots, Houston wins in a blowout.

Lay the points with Houston as it crockpots Notre Dame en route to a massive victory.

Pick: Houston -16.5 (Play to -18)

About the Author
College hoops enthusiast with a very exciting day job.

Follow Ky McKeon @Ky_3MW on Twitter/X.

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