College Basketball Odds, Pick for Louisville vs Indiana on Wednesday

College Basketball Odds, Pick for Louisville vs Indiana on Wednesday article feature image
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Photo by David Berding/Getty Images. Pictured: Mike Woodson (Indiana)

Wednesday's college basketball odds board offers a 61-game schedule, with five 12 p.m. ET matchups starting the slate.

And while most games on a typical Wednesday, especially during the day, get passed over by recreational bettors, today will be different.

With many traveling before tomorrow's Thanksgiving holiday, bettors may turn to college basketball action to help pass the time spent in cars, on planes, etc.

As a result, I turned to Action PRO's premium picks and betting tools to help unearth the sharpest early college basketball pick for Wednesday.

I quickly landed on a game between two higher-profile programs: Louisville vs. Indiana (ESPN).

Sharpest College Basketball Pick for Louisville vs. Indiana

*College basketball odds as of Wednesday morning

As of this writing, Indiana has garnered 80% of the spread tickets as a 2.5-point favorite against Louisville.