Wyoming vs. Santa Clara Odds, Pick, Prediction: Wednesday’s College Basketball Matchup Landing Wiseguy Action

PJ Walsh

Nov 30, 2022, 02:23 PM EST

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Wyoming vs. Santa Clara Odds, Pick, Prediction: Wednesday’s College Basketball Matchup Landing Wiseguy Action article feature image

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Photo by Ethan Miller/Getty Images. Pictured: Head coach Herb Sendek of the Santa Clara Broncos

Thursday's college basketball schedule rolls on with Wyoming taking on Santa Clara at 4 p.m. ET.
Live college basketball odds show Santa Clara as a 6.5-point spread favorite over Wyoming, with the over/under sitting at 136.5.
Below we break down the smartest college basketball pick for Wyoming vs. Santa Clara on Wednesday afternoon.

Wyoming vs. Santa Clara Odds

Wyoming Odds	+6.5
Santa Clara Odds	-6.5
Over/Under	136.5
Date	Wednesday, Nov. 30
Time	4 p.m. ET
Channel	FloSports

*Odds as of Wednesday morning

Wednesday's Wyoming vs. Santa Clara college basketball is extremely interesting from a betting market perspective.

To start, a key injury has shaken up what to expect in this matchup.

And as is usually the case, savvy bettors are using news of this injury to find value in an otherwise low-profile college basketball game.

So let's go ahead and dive into how injury news is affecting Wyoming vs. Santa Clara odds and, more importantly, how bettors are taking advantage right now.