Tonight, we will dial up a three-team parlay for Champions Week. We will start this parlay in Indianapolis for a battle between the Iowa Hawkeyes and the Ohio State Buckeyes.
Then, we will head to the World's Most Famous Arena for leg two of this parlay. Madison Square Garden will host a matchup between the Georgetown Hoyas and the DePaul Blue Demons.
Finally, we will go to Charlotte, North Carolina, for the final leg of this parlay. The Syracuse Orange will clash with the SMU Mustangs in round two of the ACC Tournament.
College Basketball Parlay for Wednesday, March 12
With the matchups set, let's dive into my college basketball picks and NCAAB parlay for Wednesday, March 12.
College Basketball Picks, Parlay
- Ohio State ML -218 vs. Iowa
- Georgetown -4.5 (-112) vs. DePaul
- Syracuse +9.5 (-115) vs. SMU
Parlay Odds: +416 via DraftKings
Remember that some parlays are long shots for a reason, so please bet responsibly.

Ohio State ML -218
6 p.m. ET · Peacock
Iowa comes into the tournament with a record of 16-15. The season has been disappointing in Iowa City.
The Hawkeyes got uncompromising news early in the year when star big man Owen Freeman was injured and would miss the rest of the season. Freeman led the team with 16.7 points per game and 6.7 rebounds.
The only chance for Iowa to go dancing this season will be to go on a Cinderella run and win the Big Ten Championship. Senior Payton Sandfort leads the team with 16.3 points and 6.3 rebounds.
Ohio State has posted a record of 17-14. The Buckeyes are on the bubble and need a win tonight to improve their odds of going dancing. Ohio State has not gone dancing since 2022. Jake Diebler's team went 9-11 in Big Ten play this season.
The Buckeyes are coming off a 66-60 loss against Indiana. Junior Bruce Thornton leads the team with 17.5 points per game and 4.5 assists.
We will kick off this parlay with the Buckeyes on the moneyline. Iowa has struggled on the defensive end all season and will struggle again tonight to slow down the Buckeyes.
The Hawkeyes have been a significant fade as an underdog this season with a record of 2-13 SU.

Georgetown -4.5
6:30 p.m. ET · Peacock
DePaul has struggled again this season with a record of 13-18. The Blue Demons have been the worst team in the Big East over the past two decades. DePaul has not reached March Madness since 2004. Junior CJ Gunn leads the squad with 12.8 points per game.
Georgetown comes into the contest with a record of 17-14. The Hoyas will need to go on a miracle run to go dancing, but they saw improvements this season under second-year head coach Ed Cooley. Cooley will attempt to bring the winning culture back to this program.
Since 2016, Georgetown has gone dancing just once, when they won the Big East Tournament in 2021. The Hoyas went 8-12 in the Big East this season. TCU transfer Micah Peavy leads the team with 16.9 points per game.
DePaul has been a tremendous fade this season with a 7-13 record as an underdog ATS, and the Blue Demons are one of the worst defensive teams in the conference. They allow opponents 74.1 points per game, which ranks 258th in the nation.
Georgetown, meanwhile, has been strong on the defensive side of the floor. The Hoyas allow opponents 68.7 points per game, ranking 110th in the nation.
DePaul has struggled taking care of the basketball (12.2 turnovers per game) and now faces a Georgetown defense that ranks 35th in the nation in turnovers forced per game. The Hoyas will lock down the DePaul offense and cruise to a cover tonight.

Syracuse +9.5
9:30 p.m. ET · ESPNU
Syracuse is coming off a hard-fought upset win over Florida State last night. The Orange have a record of 14-18, including 7-13 in ACC play. Syracuse has not reached the big dance since 2021. Junior J.J. Starling leads the team with 17.9 points per game and 2.9 assists.
SMU has a record of 22-9. The Mustangs feel they have done enough to earn the right to go dancing. This season, SMU went 13-7 in a weak ACC conference.
Andy Enfield's team has not reached the March Madness tournament since 2017. Wake Forest transfer Boopie Miller leads the team with 13.4 points per game and 5.7 assists.
The Orange will fight with their season on the line tonight. Syracuse has been playing much better basketball on the offensive side of the floor lately, averaging 80.6 points per game over their past nine games.
We just saw these two teams clash on March 4th, where the Orange competed on the road, losing 77-75. Tonight, we will see a close back-and-forth contest that favors the underdog.