Duke vs. Michigan State Odds, Opening Spread, Predictions for March Madness 2022

Duke vs. Michigan State Odds, Opening Spread, Predictions for March Madness 2022 article feature image
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Grant Halverson/Getty Images. Pictured: Paolo Banchero and Wendell Moore.

Duke vs. Michigan State Odds

Duke Odds-7
Michigan State Odds+7
Over/Under144
Opening spread and over/under via FanDuel. Find more March Madness odds here.

The madness marches on as we roll into the second round of the 2022 NCAA Tournament, featuring No. Higher Duke against No. Lower Michigan St.. Find our expert's projected odds and more about how these teams match up ahead of the Round of 32 below.

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Projected Duke vs. Michigan State Odds

Projected Duke Odds-6.5
Projected Michigan State Odds+6.5
Projected Over/Under141.5
March Madness projections as of Selection Sunday. Find the latest NCAA Tournament projections here.

Duke vs. Michigan State Matchup Matrix

Toggle the dropdowns below to hide or show how Duke and Michigan State match up statistically. Data via KenPom as of Sunday, March 13:

Duke Offense vs. Michigan State Defense
Offense
Defense
Edge
eFG%1469
Turnover %17328
Rebound Rate58112
Free Throw Rate255105

Michigan State Offense vs. Duke Defense
Offense
Defense
Edge
eFG%8536
Turnover %274296
Rebound Rate80203
Free Throw Rate1602

Pace of Play
Tempo160128
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More About Duke

Kody Malstrom: Duke may not be the powerhouse it once appeared to be, but don’t be fooled. The Blue Devils are still far-and-away the No. 1 team in the ACC.

With five weapons on the floor at all times, the Blue Devils have one of the most versatile offensive attacks in the nation.

ACC freshman phenom Paolo Banchero has star ability, and he will look to lead Duke on a run. He averaged 17.1 points, 7.7 rebounds and 3.1 assists per game during the regular season.

Banchero doesn’t have to do it himself, though, as this team is loaded with talent.

Wendell Moore Jr. has been a viable No. 2 all season, scoring 13.1 points per game. Three others are also putting up points in the double digits, including Trevor Keels, Mark Williams and AJ Griffin.

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More About Michigan State

Stuckey: This is not one of Tom Izzo’s stronger teams. The Spartans just seem a bit short on talent and have major issues in the turnover department on both ends of the floor.

Michigan State ranks 259th in turnover percentage on offense and 329th on defense. Yes, it won 22 games headed into the weekend but it’s buoyed by a lot of luck. There’s a reason Shot Quality has MSU as one of the five luckiest teams in the country with a projected record of 15-17 based on quality of shots.

Shooting regression looms for a Sparty team that led the Big Ten in both 3-point shooting (38.3%) and 3-point defense (32..0%) during league play. Michigan State’s KenPom rank sits around 40, which seems like a pretty fair measure of where this team sits headed into the tourney.

The Spartans do have a lot of size and will battle on the glass, but Izzo March Magic can likely only take this team so far. – Stuckey

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