Louisville vs Indiana Odds, Picks, Predictions for Wednesday, November 27

Louisville vs Indiana Odds, Picks, Predictions for Wednesday, November 27 article feature image
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Photo by Bryan Lynn/Icon Sportswire via Getty Images. Pictured: Myles Rice (Indiana)

The Louisville Cardinals take on the Indiana Hoosiers in Nassau, Bahamas, as part of the Battle 4 Atlantis. Tip-off is set for 12 p.m. ET on ESPN.

The Hoosiers are favored by 2.5 points on the spread with a moneyline of -142. The total is set at 154 points.

Here’s my Louisville vs. Indiana predictions and college basketball picks for November 27, 2024.


Louisville vs Indiana Prediction

My Pick: Indiana -1.5

My Louisville vs Indiana best bet is on the Hoosiers spread, with the best odds currently available at FanDuel. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.


Louisville vs Indiana Odds

Louisville Logo
Wednesday, Nov. 27
12 p.m. ET
ESPN
Indiana Logo
Louisville Odds
SpreadTotalMoneyline
+2.5
-108
154
-112 / -108
+120
Indiana Odds
SpreadTotalMoneyline
-2.5
-112
154
-112 / -108
-142
Odds via DraftKings. Get up-to-the-minute NCAAB odds here.
DraftKings Logo
  • Louisville vs Indiana spread: Indiana -2.5
  • Louisville vs Indiana over/under: 154 points
  • Louisville vs Indiana moneyline: Indiana -142, Louisville +120
  • Louisville vs Indiana best bet: Indiana -1.5

Spread

I like Indiana on the spread up to 6.

Moneyline

I'm avoiding the moneyline.

Over/Under

I'm passing on the total.

My Pick: Indiana -1.5 (Play to -6)

Louisville vs Indiana College Basketball Betting Preview

The Battle 4 Atlantis tips off on Wednesday with two teams that could really use a statement win. Pat Kelsey is searching for his first big victory at Louisville, and Mike Woodson looks to restore faith that this could be the year for Indiana fans.

Indiana enters this game with a flawless 4-0 record, but the Hoosiers have had a handful of uninspiring halves along the way, trailing Eastern Illinois after 20 minutes and letting UNC Greensboro hang around for far too long.

On the other end, Louisville has been business-like in its three wins, disposing of Winthrop, Bellarmine and Morehead State by comfortable margins.

The Cardinals' lone game against an NCAA Tournament-caliber squad was ugly though, as Tennessee slaughtered Kelsey's squad in their home gym (days after Kelsey promoted videos of himself encouraging fans to "Pack the Yum").

It remains to be seen if Kelsey's crowd-begging skills will translate to Atlantis, or if his teams can win games against quality opponents even if they have the crowd advantage. Kelsey's teams are just 3-27 outright in 30 career games against KenPom top-75 opponents.

Louisville wants to shoot as many 3s as possible, as Kelsey's teams always do. On the season, the Cardinals rank second nationally in 3-point attempt rate, but the shots aren't falling just yet.

The Cardinals make only 29% from 3 as a team, a whopping 6% worse than an Indiana team that is often criticized for its inability to shoot.

This year's game could be decided by star power, and Indiana has the decisive advantage in that category. Woodson's transfer portal class features point guard Myles Rice — who has been the Hoosiers' best player in their brightest moments this season — and former Arizona center Oumar Ballo.

There is an argument to be made that Indiana has the four best players in this game, as two of Louisville's biggest stars (Kasean Pryor and Terrence Edwards Jr.) have both logged single-digit points in multiple games already this season.

Given Kelsey's track record in big games and Indiana's advantage physically, the safe bet is on the Hoosiers to cover.

About the Author
Greg Waddell writes college basketball previews for The Action Network and is a featured guest on the BBOC podcast. He has been betting on sports for 10 years and has worked in sports betting since 2022.

Follow Greg Waddell @gwizzy12 on Twitter/X.

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