The McNeese Cowboys take on the Purdue Boilermakers in the NCAA Tournament. Tip-off is set for 12:10 p.m. on CBS.
Purdue is favored by 6.5 points on the spread with a moneyline of -245. The total is set at 143.5 points.
Here’s my McNeese vs. Purdue predictions and college basketball picks for March 22, 2025.
McNeese vs Purdue Prediction
My Pick: Purdue -6 (Play to -8.5)
My McNeese State vs Purdue best bet is on the Boilermakers spread, with the best odds currently available at Caesars. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
McNeese vs Purdue Odds
| McNeese Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6.5 -118 | 143.5 -105o / -110u | +200 |
| Purdue Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6.5 -102 | 143.5 -105o / -110u | -245 |
- McNeese vs Purdue spread: Purdue -6.5
- McNeese vs Purdue over/under: 143.5 points
- McNeese vs Purdue moneyline: Purdue -245, McNeese +200
- McNeese vs Purdue best bet: Purdue -6 (Play to -8.5)
Spread
I'm taking the Boilermakers on the spread, as they should win this game by 10+.
Moneyline
There's no value on the moneyline.
Over/Under
I have no play on the total.
My Pick: Purdue -6 (Play to -8.5)
McNeese vs Purdue College Basketball Betting Preview
After upsetting 5-seeded Clemson 69-67 on Thursday, 12-seeded McNeese takes on Purdue in Providence, RI.
The final score of the Clemson-McNeese game appears closer than it actually was, as the Cowboys were up 40-16 at one point and dominated from start to finish.
Brandon Murray led McNeese with 21 points on 10-of-18 shooting from the field.
Yes, that win versus Clemson was impressive, but I don’t think the Cowboys can repeat that performance versus Matt Painter and the Purdue Boilermakers.
Purdue looked solid in its Round of 64 game versus High Point. I took Purdue -7.5 that game and cashed it, as Purdue won by 12, 75-63. Trey Kaufman-Renn led the squad with 21 points and shot 10-of-16 from the field.
Looking at this upcoming matchup, I think that the Boilermakers are just too deep for McNeese. Big Ten Player of the Year Braden Smith is in peak form and Purdue matches up well against Will Wade’s team.
Both of these teams like to play slow, but if Purdue’s offense can limit turnovers and knock down its 3s, I don’t see how it doesn't win by 10+.
Expect Purdue to make a statement, as I can see McNeese becoming a popular pick on Saturday. Not for me, though.
