Michigan vs UC San Diego Odds, Opening Spread, Predictions for 2025 NCAA Tournament

Michigan vs UC San Diego Odds, Opening Spread, Predictions for 2025 NCAA Tournament article feature image
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Tre Donaldson #3 of the Michigan Wolverines (Photo by Michael Reaves/Getty Images)

Michigan vs. UC San Diego Odds

Michigan Logo
Thursday, Mar. 20
10 p.m. ET
TBS
UC San Diego Logo
Michigan Odds
SpreadTotalMoneyline
-2.5
-118
140.5
-110o / -110u
-162
UC San Diego Odds
SpreadTotalMoneyline
+2.5
-102
140.5
-110o / -110u
+136
Odds via DraftKings. Get up-to-the-minute NCAAB odds here.
DraftKings Logo

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The 2025 NCAA Tournament field has been announced and Michigan will take on UC San Diego in the first round of the South region. Here's everything you need to know about Michigan vs. UC San Diego odds, spread and more.

Michigan opened as a -2.5-point favorite over UC San Diego in the first round of the NCAA Tournament. The total is set at over/under 140.5 points scored by both teams combined.

Find out how No. 5-seeded Michigan and No. 12-seeded UC San Diego match up ahead of their opening round matchup.


Michigan vs. UC San Diego Analysis

This is an absolute smash spot for the Tritons here. 

Michigan, coming off of a tiring four days in Indianapolis, will undoubtedly have some fatigue against a scorching red-hot UC San Diego team out of the Big West.

Michigan has compiled 12 (!) wins by four points or less throughout the regular season. The Wolverines are a ticking time bomb in my eyes, and the Tritons will most likely be my favorite bet of the Round of 64. 

Tritons +3.5 has popped up at a couple of shops already, and I will happily snag that now with some additional sprinkling on the moneyline.  

–John Feltman


For more coverage of the 2025 NCAA Tournament and Selection Sunday, make sure to check out our experts' live reactions to the bracket reveal and the Selection Sunday live show, where you can get their instant analysis on every matchup as well as some early insights to help you make your bets.

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