Missouri vs. Drake Odds, Opening Spread, Predictions for 2025 NCAA Tournament

Missouri vs. Drake Odds, Opening Spread, Predictions for 2025 NCAA Tournament article feature image
Credit:

(Photo by Matthew Maxey/Icon Sportswire via Getty Images via Getty Images)

Missouri vs. Drake Odds

Missouri Logo
Thursday, March 20, 2025
7:35 p.m. ET
TruTV
Drake Logo
Missouri Odds
SpreadTotalMoneyline
-6
-110
133
-110/-110
+235
Drake Odds
SpreadTotalMoneyline
+6
-110
133
-110/-110
-190
Odds via DraftKings. Get up-to-the-minute NCAAB odds here.
DraftKings Logo

Click Here to Bet Missouri Instantly at DraftKings! | Click Here to Bet Drake Instantly at DraftKings!

The 2025 NCAA Tournament field has been announced and Missouri will take on Drake in Round 1 of the West region. Here's everything you need to know about Missouri vs. Drake odds, spread and more.

Missouri opened as a -5-point favorite over Drake in the first round of the NCAA Tournament. The total is set at over/under 133 points scored by both teams combined.

Find out how No. 6-seeded Missouri and No. 11-seeded Drake match up ahead of their opening round matchup.


Missouri vs. Drake Analysis

Well, this matchup sucks for this Tiger fan. Drake is legit and 2-0 against power-conference competition this year (Vanderbilt and Kansas State). It’s a stark contrast of style, with Drake taking the air out of the ball and playing the slowest tempo in the country and Mizzou looking to get out, run and shoot plenty of 3s.

Drake’s methodical attack could befuddle a Tiger squad that has had issues getting lost on this end of the floor countless times. Princeton smacked Mizzou two years ago in the Big Dance, and Drake could do the same thing.

The one feather in Mizzou’s cap is its massive athleticism edge. Outside of Cam Manyawu, Drake doesn't have close to the caliber of athletes that permeates throughout Missouri’s roster. Mizzou could pound the ball inside, harass the excellent Bennett Stirtz as he keys the offense, and outrun the Bulldogs going the other way.

It will take a big game from Mark Mitchell, a competent rotation from Dennis Gates, and a decent shooting day from deep for the Tiger snipers. Take Drake plus the points — the Bulldogs are just too good and play too slow to get beat by more than a couple of possessions.

The Pick: Drake ATS

— Ky McKeon


For more coverage of the 2025 NCAA Tournament and Selection Sunday, make sure to check out our experts' live reactions to the bracket reveal and the Selection Sunday live show, where you can get their instant analysis on every matchup as well as some early insights to help you make your bets.

About the Author
Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

Follow Action Network Staff @ActionNetworkHQ on Twitter/X.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.