Mount St. Mary’s vs Duke Predictions, Odds, Time: 2025 March Madness Picks

Mount St. Mary’s vs Duke Predictions, Odds, Time: 2025 March Madness Picks article feature image
Credit:

Lance King/Getty Images. Pictured: Duke’s Cooper Flagg.

Starting soon
Odds Updating Soon
Matchup - 3/21 6:50pm UTCSpreadTotalMoneyline
+32.5-111
o141.5-105
+3617
-32.5-110
u141.5-115
-10000

The Mount St. Mary's Mountaineers take on the Duke Blue Devils in the NCAA Tournament. Tip-off is set for 2:50 p.m. ET on CBS.

Duke is favored by 32 points on the spread with a moneyline of -20000. The total is set at 141 points.

Here are my Mount St. Mary's vs. Duke predictions and college basketball picks for March 21, 2025.


Mount St. Mary's vs Duke Prediction

My Pick: 1H Under 66.5

My Mount St. Mary's vs Duke best bet is on both teams to stay under the first-half total, with the best odds currently available at BetRivers. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.


Mount St. Mary's vs Duke Odds, Spread, Pick

Mount St. Mary's Logo
Friday, March 21
2:50 p.m. ET
CBS
Duke Logo
Mount St. Mary's Odds
SpreadTotalMoneyline
+32
-110
141
-110o / -110u
+2800
Duke Odds
SpreadTotalMoneyline
-32
-110
141
-110o / -110u
-20000
Odds via bet365. Get up-to-the-minute NCAAB odds here.
bet365 Logo
  • Mount St. Mary's vs Duke spread: Duke -32
  • Mount St. Mary's vs Duke over/under: 141 points
  • Mount St. Mary's vs Duke moneyline: Duke -20000, Mount St. Mary's +2800
  • Mount St. Mary's vs Duke best bet: 1H Under 66.5

My Mount St. Mary's vs Duke NCAA Tournament Betting Preview

A 16-seed has beaten a 1-seed only twice in the history of the NCAA Tournament. So, it's safe to say that the Mount St. Mary's Mountaineers are not expected to be very competitive in this one.

The spread is also indicative of that, as the Duke Blue Devils are favored by 32.5. While the spread is steep, Duke's sizable advantages create value on another angle.