NCAA Tournament Odds, Pick for Arizona vs Duke in Sweet 16 (Thursday, March 27)

NCAA Tournament Odds, Pick for Arizona vs Duke in Sweet 16 (Thursday, March 27) article feature image
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Photo by Jacob Kupferman/Getty Images. Pictured: Cooper Flagg #2 of the Duke Blue Devils reacts

After four days of NCAA Tournament action, college basketball fans get to take a breather ahead of Thursday's Sweet 16 matchups.

However, the work for college basketball bettors doesn't stop, as NCAA Tournament odds are open for business for all eight Sweet 16 games.

While there's still plenty of time for bettors to handicap each of these games for the smartest NCAA Tournament picks, Action PRO's cutting-edge tools have already sniffed out an under-the-radar bet that professionals are making for Arizona vs. Duke on Thursday night (9:39 p.m. ET, CBS).

Below, we detail how the sharps are approaching this Sweet 16 matchup.

NCAA Tournament Odds, Sharpest Pick for Arizona vs. Duke

*Odds as of Monday morning

Duke is a 9.5-point spread favorite against Arizona, with Thursday's over/under sitting at 153.5, according to live NCAA Tournament odds.

And if you blinked, you may have missed the quick burst of wiseguy action that hit this game shortly after the odds opened.