Ohio State vs Purdue Odds, Picks, Predictions

Ohio State vs Purdue Odds, Picks, Predictions article feature image
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Photo by John Fisher/Getty Images. Pictured: John Mobley Jr. (Ohio State)

The Ohio State Buckeyes take on the Purdue Boilermakers in West Lafayette, IN. Tip-off is set for 7:30 p.m. ET on Peacock.

Purdue is favored by 10 points on the spread with a moneyline of -550. The total is set at 141 points.

Here’s my Ohio State vs. Purdue predictions and college basketball picks for January 21, 2025.


Ohio State vs Purdue Prediction

My Pick: Ohio State +10.5 (Play to +9)

My Ohio State vs Purdue best bet is on the Buckeyes spread, with the best odds currently available at BetRivers. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.


Ohio State vs Purdue Odds

Ohio State Logo
Tuesday, Jan. 21
7:30 p.m. ET
Peacock
Purdue Logo
Ohio State Odds
SpreadTotalMoneyline
+10
-108
141
-110o / -110u
+400
Purdue Odds
SpreadTotalMoneyline
-10
-112
141
-110o / -110u
-550
Odds via bet365. Get up-to-the-minute NCAAB odds here.
bet365 Logo
  • Ohio State vs Purdue spread: Purdue -10.5
  • Ohio State vs Purdue over/under: 141 points
  • Ohio State vs Purdue moneyline: Purdue -550, Ohio State +400
  • Ohio State vs Purdue best bet: Ohio State +10.5 (Play to +9)

My Ohio State vs Purdue NCAAB Betting Preview

After losing three of four in December, there were questions about the future of the Boilermakers.

Were they just an average Big Ten team without Zach Edey? Would turnovers again be their bugaboo in the now 18-team Big Ten?

Well, Matt Painter and Co. turned things around in the New Year, as the Boilermakers have won seven straight games and are currently in sole position of second place in the Big Ten.

The Boilermakers have looked impressive in the process, too, pummeling Northwestern, Rutgers and Nebraska before sweeping a West Coast road trip (Washington, Oregon).

Meanwhile, Ohio State has had a topsy turvy season. A win over Kentucky inspired progress for Jake Diebler’s bunch, but injuries and absences have derailed the train as of late.

(Meechie Johnson Jr. has been away from the team due to personal reasons, Aaron Bradshaw was being investigated for a domestic incident and now Devin Royal is injured.)

Also, the Buckeyes have lost four of five, including a home defeat to Indiana.

While it would seem like Purdue has the upper hand heading into this game (especially at Mackey Arena), I’m actually going to back the Buckeyes.

It’s dangerous proposition to fade Big Ten home teams (especially two in one night); however, I believe 10 points is way too many in this spot.

Ohio State is eighth in the country in potential breakaway points off steals, via Haslametrics, and the Boilermakers have shown in the past that turnovers can be a problem.

If Royal does play, this spread becomes a massive bargain.

If he doesn’t, I still like Ohio State at +10, but I would be more cautious with how many units I would place.

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