2021 NCAA Tournament Odds: Our Projected Spreads, Totals for Every First-Round Matchup

2021 NCAA Tournament Odds: Our Projected Spreads, Totals for Every First-Round Matchup article feature image
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Jamie Squire/Getty Images. Pictured: Cade Cunningham

  • We've projected odds for every 2021 NCAA Tournament first-round game. Use them to bet, or get help with your bracket picks.
  • Use our PRO Projections tool to compare these lines to spreads posted at sportsbooks to find an edge.
  • The 2021 NCAA Tournament tips off Wednesday with First Four games, and the first full day is Friday, March 19.

The NCAA Tournament field is set, and with it comes one of the best betting months of the year.

Sportsbooks will slowly start to trickle out spreads over the next few hours, but our resident oddsmaker Sean Koerner has already projected every spread and total.

You can find can find betting edges on NCAA Tournament games using our PRO Projections tool, which compares our lines to the lines posted by sportsbooks.

West Region

Top left corner of bracket.

TeamSpreadTotal
1. GonzagaN/A
16. App State/Norfolk State
8. Oklahoma-1.5141.7
9. Missouri1.5
5. Creighton-8.5143.3
12. UCSB8.5
4. Virginia-8.5141.1
13. Ohio8.5
6. USCN/AN/A
11. Wichita State/Drake
3. Kansas-13.5144.6
14. Eastern Wash13.5
7. Oregon-3.5137.1
10. VCU3.5
2. Iowa-19146.5
15. Grand Canyon19

East Region

Bottom left corner of bracket

TeamSpreadTotal
1. MichiganN/AN/A
16. Mount St. Mary's/Texas Southern
8. LSU-0.5147.4
9. St. Bonaventure0.5
5. Colorado-6138.2
12. Georgetown6
4. Florida St-12143.4
13. UNC Greensboro12
6. BYUN/AN/A
11. UCLA/Michigan State
3. Texas-10.5135.7
14. Ab Christian10.5
7. UConn-1133.7
10. Maryland1
2. Alabama-18.5139.2
15. Iona18.5

South Region

Top right corner of bracket

TeamSpreadTotal
1. Baylor-29149.4
16. Hartford29
8. UNC-1.5141.7
9. Wisconsin1.5
5. Villanova-8.5143.3
12. Winthrop8.5
4. Purdue-8.5141.1
13. North Texas8.5
6. Texas Tech-6139.9
11. Utah State6
3. Arkansas-13.5144.6
14. Colgate13.5
7. Florida-3.5137.1
10. VA Tech3.5
2. Ohio State-19146.5
15. Oral Roberts19

Midwest Region

Bottom right corner of bracket

TeamSpreadTotal
1. Illinois-22.5143.8
16. Drexel22.5
8. Loyola (IL)-1130.7
9. GA Tech1
5. Tennessee-8131.4
12. Oregon St8
4. OK State-8138.9
13. Liberty8
6. San Diego State-3139.2
11. Syracuse3
3. West Virginia-14137.9
14. Morehead St14
7. Clemson2125.2
10. Rutgers-2
2. Houston-20.5131.5
15. Cleveland St20.5
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