The Purdue Boilermakers take on the Indiana Hoosiers in Bloomington. Tip-off is set for 1:30 p.m. ET on CBS.
Purdue is favored by 3.5 points on the spread with a moneyline of -175. The total is set at 150.5 points.
Here are my Purdue vs. Indiana predictions and college basketball picks for February 23, 2025.
Purdue vs Indiana Prediction
My Pick: Purdue -3.5 (Play to -5)
My Purdue vs Indiana best bet is on the Boilermakers spread, with the best odds currently available at DraftKings. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Purdue vs Indiana Odds
| Purdue Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3.5 -110 | 150.5 -115o / -105u | -175 |
| Indiana Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3.5 -110 | 150.5 -115o / -105u | +145 |
- Purdue vs Indiana spread: Purdue -3.5
- Purdue vs Indiana over/under: 150.5 points
- Purdue vs Indiana moneyline: Purdue -175, Indiana +145
- Purdue vs Indiana best bet: Purdue -3.5 (Play to -5)
Spread
I'm taking the Boilers on the spread. Purdue has the edge, and Matt Painter should coach circles around Mike Woodson.
Moneyline
While I'm taking Purdue to cover, I don't see value on the moneyline.
Over/Under
I don't have a play on the total.
My Pick: Purdue -3.5 (Play to -5)
Purdue vs Indiana College Basketball Betting Preview
Purdue looked like the eventual Big Ten champion just 15 days ago, but three straight losses have knocked the Boilermakers out of first and into danger of falling out of the top four of the league. A top-four seed in the Big Ten Tournament means a double-bye to the quarterfinals — crucial for a Big Ten Conference Tournament title run.
Indiana’s NCAA Tournament hopes aren’t totally dead, but the Hoosiers need to focus on making the Big Ten Dance if they want to make the big one.
The top 15 teams make the conference tourney, and IU sits just 1.5 games above the cut line. The Hoosiers have lost six of their last seven and eight of their last 10.
Game 1 between these two squads was much closer than expected. IU led by six with just over five minutes to play at Mackey Arena and nearly pulled a major upset against its bitter rival.
Purdue shot just 2-of-13 from deep in that one (64% inside the arc), but IU’s 20 turnovers turned out to be the difference.
The game should give the Hoosiers confidence, and their glass crash was effective, as was their inside-the-arc attack.
But catching an angry Boilers squad off three losses at Assembly Hall — a place where IU has already dropped four conference games this year — doesn’t bode well.
Purdue works the ball so well on the offensive end.
Braden Smith is a star and arguably the best point guard in the country. Big man Trey Kaufman-Renn has been a stud as the fulcrum of the Boiler offense.
Head coach Matt Painter plays through the post on offense, and his Boilers run a ton of pick-and-roll to complement their sharpshooting wings.
Mistakes are rare on this end of the floor, making Purdue incredibly tough to beat if you’re an undisciplined defensive team. IU has been called that once or twice.
IU’s post defense has been brutal this year, ranking 345th nationally in PPP allowed, per Synergy. With so much frontcourt size and depth, it’s quite sad how bad IU is at protecting the paint. Purdue should slice and dice here.
Indiana likes to play through the block as well, and though Purdue’s post-up defense has been good this season, it severely lacks rim protection and ranks just 342nd in field-goal percentage allowed at the rim (IU leads the country in FG% at the rim).
Painter will look to keep the ball out of the paint with scheme and dig-downs, unafraid of Indiana’s poor-shooting perimeter.
IU should look to pound the rock toward the rim all game. But of course, it will settle for midrange looks as it has all season and refuse to feed the meter inside.
The Hoosiers are more uptempo than the Boilers, but their guard play doesn’t compare.
While Purdue can be beaten in transition with its lack of perimeter length and athleticism, Indiana has ball security issues, and the Boilers have been getting their hands on everything in league play.
Revenge is a strong motivator, but Purdue is simply the much better team, and much of that is coaching.
Painter should run circles around Mike Woodson. Indiana can stick around with Purdue with its size and style, but the Boilers should pull away and eventually put this one to bed. Hoosier fans should be getting their “boo” muscles warmed up.
