The Villanova Wildcats take on the USC Trojans in the College Basketball Crown. Tip-off is set for 9:30 p.m. ET on FS1.
Villanova is favored by 5.5 points on the spread with a moneyline of -250. The total is set at 150.5 points.
Here are my Villanova vs. USC predictions and college basketball picks for April 3, 2025.
Villanova vs USC Prediction
My Pick: Villanova -5.5
My Villanova vs USC best bet is on the Wildcats spread, with the best odds currently available at DraftKings. For all of your college basketball bets, find the best lines using our live NCAAB odds page.
Villanova vs USC Odds
| Villanova Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-5.5 -115 | 150.5 -105o / -115u | -250 |
| USC Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+5.5 -105 | 150.5 -105o / -115u | +205 |
- Villanova vs USC spread: Villanova -5.5
- Villanova vs USC over/under: 150.5 points
- Villanova vs USC moneyline: Villanova -250, USC +205
- Villanova vs USC best bet: Villanova -5.5
Spread
I'll back the Wildcats as two-possession favorites.
Moneyline
I'm passing on the moneyline.
Over/Under
I'm passing on the over/under.
My Pick: Villanova -5.5
Villanova vs USC College Basketball Betting Preview
I’ve been reasonably impressed with USC’s offense in the latter half of the season. The Trojans are excellent in downhill dribble creation and have finished well at the rim.
